急性胰腺炎合并席汉氏综合征：1例病例报道并文献复习

刘大晟; 刘丽; 甘峰; 吴先林; 叶刚

doi:10.24920/003574

Your Location：

Home >

Browse articles >

急性胰腺炎合并席汉氏综合征：1例病例报道并文献复习

中国医学科学杂志（英文版） 2020年35卷第1期页码：95-100

Case Report | Updated：2024-04-10

- 急性胰腺炎合并席汉氏综合征：1例病例报道并文献复习
- Affiliations：
  
  1Department of Vascular and Thyroid Surgery, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China
  2Outpatient Department, Guangzhou 510632, China
  3School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China
  4Center for Diagnosis and Treatment of Pancreatic Disease, Guangzhou 510632, China
  5Department of Gastroenterology, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China
- Author bio：
  
  * E-mail: dr.yegang@qq.com
- Funds：
  
  This study was supported by the Fundamental Research Funds for the Central Universities(21614306);National Natural Science Foundation of China(81403302);Administration of Traditional Chinese Medicine of Guangdong Province, China(20131152);Medical Scientific Research Foundation of Guangdong Province, China(2011336)
- DOI：10.24920/003574
  中图分类号：
- 收稿日期：2019-05-18，
  
  网络出版日期：2020-03-31，
  
  纸质出版日期：2020-02-20
- Accepted：
Scan QR Code
刘大晟, 刘丽, 甘峰, 等. 急性胰腺炎合并席汉氏综合征：1例病例报道并文献复习[J]. 中国医学科学杂志（英文版）, 2020,35(1):95-100.

Liu Dasheng, Liu Li, Gan Feng, et al. Acute Pancreatitis Complicated by Sheehan's Syndrome: A Case Report and Literature Review[J]. Chinese medical sciences journal, 2020, 35(1): 95-100.
刘大晟, 刘丽, 甘峰, 等. 急性胰腺炎合并席汉氏综合征：1例病例报道并文献复习[J]. 中国医学科学杂志（英文版）, 2020,35(1):95-100. DOI： 10.24920/003574.

Liu Dasheng, Liu Li, Gan Feng, et al. Acute Pancreatitis Complicated by Sheehan's Syndrome: A Case Report and Literature Review[J]. Chinese medical sciences journal, 2020, 35(1): 95-100. DOI： 10.24920/003574.

摘要

44岁女性因持续上腹部疼痛2天和意识障碍7小时被转入暨南大学附属第一医院ICU

入院诊断为严重急性坏死性胰腺炎（高甘油三酯血症型）并发多器官功能障碍。CT检查结果仅提示小面积坏死胰腺炎

与临床表现不符合

结合患者全身毛发稀少、产后大出血既往史、及激素检查结果

患者被诊断为希汉氏综合症和垂体功能危象。给予激素替代治疗之后

患者病情迅速好转。

Abstract

A 44-year-old woman was transferred to the ICU of the First Affiliated Hospital of Jinan University for 2 days of persistent epigastric pain and 7 hours of unconsciousness. Her admission diagnosis was severe acute necrotizing pancreatitis (hypertriglyceridemia type) with multiple organ dysfunctions. The results of CT revealed a small area of necrotizing pancreatitis

which was not consistent with the severe clinical manifestations. Considering lack of hair and history of postpartum hemorrhage

hormone examination was carried out. According to the results of the examination

she was further diagnosed as Sheehan’s syndrome and pituitary crisis. After hormone replacement therapy

her condition improved rapidly.

关键词

Keywords

references

Zhang WZ , Xie JX , Shen J , et al . Hypertriglyceridemic acute pancreatitis in a patient with Sheehan’s syndrome . Hepatobiliary Pancreat Dis Int 2006 ; 5 ( 3 ): 468 - 70 .

He FQ , Huang ZW , Guo J , et al . Severe acute pancreatitis in a patient with Sheehan’s syndrome . Chin J Criti Care Medi 2007 ; 27 ( 1 ): 762 - 3 .

Shen DH , Sun GB , Luo R , et al . Sheehan’s syndrome with severe acute pancreatitis: a case report . Practical J Med Pharm 2013 ; 30 ( 2 ): 127 .

Zhen ZQ , Yang XW . Characteristic features of acute pancreatitis with Sheehan’s syndrome . Chin J Endocr Surg 2013 ; 7 ( 6 ): 515 - 6 . doi: 10.3760/cma.j.issn.1674-6090.2013.06.020 10.3760/cma.j.issn.1674-6090.2013.06.020 .

Chen YQ , Feng CL . Sheehan’s syndrome with acute pancreatitis: a case report . Chongqing Medical 2017 ; 46 ( 16 ): 2591 - 2 .

Sheehan HL . Postpartum necrosis of the anterior pituitary . J Pathol Bact 1937 ; 45 ( 7 ): 189 - 214 . doi: 10.1002/path.1700450118 10.1002/path.1700450118 .

Kristjansdottir HL , Bodvarsdottir SP , Sigurjonsdottir HA . Sheehan’s syndrome in modern times: a nationwide retrospective study in Iceland . Eur J Endocrinol 2011 ; 164 ( 3 ): 349 - 54 . doi: 10.1530/EJE-10-1004 10.1530/EJE-10-1004 .

Diri H , Karaca Z , Tanriverdi F , et al . Sheehan’s syndrome: new insights into an old disease . Endocrine 2016 ; 1 ( 1 ): 22 - 31 . doi: 10.1007/s12020-015-0726-3 10.1007/s12020-015-0726-3 .

Dharmshaktu P , Bhowmick J , Manglani D , et al . Recurrent symptomatic hypoglycaemia with pancytopenia as a delayed presentation of Sheehan’s syndrome with complete recovery after hormone replacement . BMJ Case Rep 2013 ; 21 ( 11 ): 9014 . doi: 10.1136/bcr-2013-009014 10.1136/bcr-2013-009014 .

Sanyal D , Raychaudhuri M . Varied presentations of Sheehan’s syndrome at diagnosis: a review of 18 patients . Indian J Endocrinol Metab 2012 ; 16 ( Suppl 2 ): S300 - 1 . doi: 10.4103/2230-8210.104067 10.4103/2230-8210.104067 .

Leonidas H , Gabriela B . A renewed focus on the association between thyroid hormones and lipid metabolism . Front Endocrinol (Lausanne) 2018 ; 9 ( 3 ): 511 - 20 . doi: 10.3389/fendo.2018.00511 10.3389/fendo.2018.00511 .

Lam KS , Chan MK , Yeung RT . High-density lipoprotein cholesterol, hepatic lipase and lipoprotein lipase activitiesin thyroid dysfunction—effects of treatment . Q J Med 1986 ; 59 ( 229 ): 513 - 21 . doi: 10.1016/0091-7435(86)90051-4 10.1016/0091-7435(86)90051-4 .

Arikan S , Bahceci M , Tuzcu A , et al . Postprandial hyperlipidemia in overt and subclinical hypothyroidism . Eur J Intern Med 2012 ; 23 : e141 - 5 . doi: 10.1016/j.ejim.2012.05.007 10.1016/j.ejim.2012.05.007 .

McGowan A , Widdowson WM , O’Regan A , et al . Postprandial studies uncover differing effects on HDL particles of overt and subclinical hypothyroidism . Thyroid 2016 ; 26 ( 3 ): 356 - 64 . doi: 10.1089/thy.2015.0443 10.1089/thy.2015.0443

Scherer J , Singh VP , Pitchumoni CS , et al . Issues in hypertriglyceridemic pancreatitis—an update . J Clin Gastroenterol 2014 ; 48 ( 3 ): 195 - 203 . doi: 10.1097/01.mcg.0000436438.60145.5a 10.1097/01.mcg.0000436438.60145.5a .

Inayat F , Zafar F , Baig AS . Hypertriglyceridemic pancreatitis treated with insulin therapy: a comparative review of 34 cases . Cureus 2018 ; 10 ( 10 ): e3501 . doi: 10.7759/cureus.3501 10.7759/cureus.3501 .

Syed H , Bilusic M , Rhondla C , et al . Plasmapheresis in the treatment of hypertriglyceridemia-induced pancreatitis: a community hospital’s experience . J Clin Apher 2010 ; 25 ( 4 ): 229 - 34 . doi: 10.1002/jca.20232 10.1002/jca.20232 .

Navina S , Acharya C , DeLany JP , et al . Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesity . Sci Transl Med 2011 ; 3 ( 107 ): 107 - 10 . doi: 10.1126/scitranslmed.3002573 10.1126/scitranslmed.3002573 .

Shahnaz AM , Shariq RM , Arshad IW , et al . Deep vein thrombosis in a patient of Sheehan’s syndrome: autoimmunity or hypercoagulabilty . Indian J Endocrinol Metab 2013 ; 17 ( Suppl1 ): S105 - 6 . doi: 10.4103/2230-8210 10.4103/2230-8210 .

Tanriverdi F , Gül A , Gül I , et al . Massive cardiac thrombosis in a patient with Sheehan’s syndrome . Endocr J 2005 ; 52 ( 6 ): 709 - 14 . doi: 10.1507/endocrj.52.709 10.1507/endocrj.52.709 .

Carr RA , Rejowski BJ , Cote GA , et al . Systematic review of hypertriglyceridemia-induced acute pancreatitis: a more virulent etiology? Pancreatology 2016 ; 16 ( 4 ): 469 - 76 . doi: 10.1016/j.pan.2016.02.011 10.1016/j.pan.2016.02.011 .

Samarasinghe S , Avari P , Meeran K , et al . Management of hypertriglyceridaemic pancreatitis in the acute setting and review of literature . BMJ Case Rep 2018 ; 11 ( 1 ): e227594 . doi: 10.1136/bcr-2018-227594 10.1136/bcr-2018-227594 .

Kandemir A , Coşkun A , Yavaşoğlu İ , et al . Therapeutic plasma exchange for hypertriglyceridemia induced acut pancreatitis: the 33 cases experience from a tertiary reference center in Turkey . Turk J Gastroenterol 2018 ; 29 ( 6 ): 676 - 83 . doi: 10.5152/tjg.2018.17627 10.5152/tjg.2018.17627 .

Stefanutti C , Labbadia G , Morozzi C . Severe hypertriglyceridemia-related acute pancreatitis . Ther Apher Dial 2013 ; 17 ( 2 ): 130 - 7 . doi: 10.1111/1744-9987 10.1111/1744-9987 .

Valdivielso P , Ramírez-Bueno A , Ewald N . Current knowledge of hypertriglyceridemic pancreatitis . Eur J Intern Med 2014 ; 25 ( 8 ): 689 - 94 . doi: 10.1016/j.ejim.2014.08.008 10.1016/j.ejim.2014.08.008 .

Song X , Shi D , Cui Q , et al . Intensive insulin therapy versus plasmapheresis in the management of hypertriglyceridemia-induced acute pancreatitis (Bi-TPAI trial): study protocol for a randomized controlled trial . Trials 2019 ; 20 ( 1 ): 365 - 71 . doi: 10.1186/s13063-019-3498-x 10.1186/s13063-019-3498-x .

Inayat F , Zafar F , Riaz I , et al . Hypertriglyceridemic pancreatitis: is insulin monotherapy a feasible therapeutic option? Cureus 2018 ; 10 ( 10 ): e3461 . doi: 10.7759/cureus.3461 10.7759/cureus.3461 .

Diri1 H , Karaca1 Z , Tanriverdi1 F , et al . Sheehan’s syndrome: new insights into an old disease . Endocrine 2016 ; 51 ( 1 ): 22 - 31 . doi: 10.1007/s12020-015-0726-3 10.1007/s12020-015-0726-3 .

浏览量

920

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

关联资源

暂无数据