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“Life sciences have entered the era of big data, uncovering the complexity of human biological systems and advancing precision medicine and scientific wellness. Here, we introduce a novel framework for Good Data Governance Practice (GDGP) coupled with a grading initiative for the life sciences, focusing on traceability and openness. The GDGP framework systematically defines governance constraints, influencing factors, and functional capabilities to streamline data governance and management efficiency. This achievement lays the groundwork for compliant cross-institutional and cross-border data sharing and collaborative processing, poised to pave the way for standardized, ethical, and scalable data-driven research in precision medicine and beyond.”

“A new review introduces research progress in the field of acute ischemic stroke. Experts have explored the dynamic processes underlying reperfusion injury and neurovascular unit disruption, emphasizing reversible changes within the penumbra and emerging imaging-guided approaches. This work lays a foundation for developing individualized neuroprotective strategies.”