“Reporting on the latest advancements in gastric cancer screening, China is making strides with the development of a high-quality screening system tailored to its national conditions. Gastric oral contrast ultrasonography (OCUS) emerges as a promising, non-invasive screening tool, offering a painless and radiation-free alternative. Expert consensus has been formed on OCUS as a preliminary screening technique, aiming to standardize its popularization. This research lays the foundation for the construction of a preliminary gastric cancer ultrasound screening system that aligns with China's national conditions.”
Gastrointestinal Ultrasound Section, Ultrasound Medicine Specialized Committee of National Health Commission Capacity Building and Continuing Education, National Major Chronic Disease Prevention and Control Innovation and Integration Pilot Project Management Committee, Gastrointestinal Ultrasound Collaborative Group, Institute of Ultrasound Medicine, Tongji University, Gastrointestinal Ultrasound Section, Ultrasound Specialized Committee, China Medical Education Association, Gastrointestinal Ultrasound Expert Committee, Chinese Ultrasound Medicine Training Project, Abdominal Specialized Committee, Chinese Association of Ultrasound in Medicine and Engineering, Ultrasound Medicine Branch of Sino-Japan Medical Science and Technology Exchange Association, Gastrointestinal Ultrasound Branch of Beijing Association of Holistic Integrative Medicine, Ultrasound Medicine Branch of China National Health Association, Chinese Anti-Cancer Association Science Popularization Committee, Ultrasound Medicine Branch of Cross-Straits Medicine Exchange Association, Engineering Research Center of Digestive Endoscopy, Minimally Invasive Diagnostic and Therapeutic Technologies, Ministry of Education
2025, 40(4): 237-252. DOI: 10.24920/004548
Abstract:The five-year survival rate of gastric cancer in China is close to those in European and North American countries but far lower than those in the Republic of Korea and Japan where national gastric cancer screening systems have been established. It is of great significance to build a high-quality gastric cancer screening system adaptive to China's national conditions. Due to the large number of people at risk of gastric cancer and the uneven distribution of medical resources, it is still difficult for China to carry out a nationwide gastroscopy screening program for gastric cancer. Gastric oral contrast ultrasonography (OCUS) is a promising, non-invasive tool for initial gastric cancer screening, offering a painless, radiation-free alternative. Based on two 2020 OCUS consensuses, this document analyzes national gastric cancer screening strategies and challenges to elaborate on the necessity, feasibility, and current problems of preliminary ultrasound screening in China. It details the key aspects of OCUS, including indications, contraindications, operator requirements, contrast agent standards, and essential scanning protocols. It also introduces the standardized ultrasound sections and the Stomach Ultrasound Report and Data System (Su-RADS) and proposes the relevant consensus opinions. After several rounds of discussions and voting by experts from multiple societies, a total of 17 consensus opinions have been formed on OCUS as a preliminary screening technique for gastric cancer, with the aim of standardizing the popularization of OCUS. In addition, the consensus calls for conducting nationwide multicenter prospective studies to improve the level of evidence and provide big data support for the construction of a preliminary gastric cancer ultrasound screening system that is in line with China's national conditions.
Keywords:oral contrast ultrasonography;gastric cancer screening;gastric contrast-enhanced ultrasound;gastric filling ultrasound;contrast agent;Stomach Ultrasound Report and Data System;expert consensus
“In the field of healthcare informatization, this study introduces its research progress. It examines China's healthcare dataset standards from 2011 to 2025, analyzing their evolution and identifying critical challenges. The study proposes a multi-faceted strategy to optimize the standard system's architecture, enhance quality and implementation, and advance data governance and intelligent service provision, laying a foundation for the construction of a robust healthcare dataset standard system.”
“In the field of xxx, expert xx has made significant research progress. By establishing the xx system/exploring the xx topic/verifying the xx conjecture, xx has provided solutions to address xx problems, opening up a new direction for research and laying the groundwork for the construction of the xx system.”
“In a cross-sectional study at Peking Union Medical College Hospital, nearly two-thirds of outpatients with chronic cancer pain were found to have chronic neuropathic cancer pain. The study identified associations with bone metastasis, radiotherapy, and voiding dysfunction, which may aid in early recognition and support the adoption of multimodal pain management strategies.”
袁博儒, 孙琛, 李默晗, 陈思, 马璐璐, 裴丽坚
2025, 40(4): 271-281. DOI: 10.24920/004542
Abstract:目的探讨慢性癌性疼痛门诊患者中慢性神经病理性癌性疼痛(chronic neuropathic cancer pain,CNCP)的患病率、分布特征及相关临床因素,为早期识别和规范化管理提供依据。方法本横断面研究于2025年6月至10月在北京协和医院疼痛门诊连续纳入符合国际疼痛研究学会(the International Association for the Study of Pain,IASP)慢性癌性疼痛诊断标准的患者。依据神经病理性疼痛特别兴趣小组(the Neuropathic Pain Special Interest Group,NeuPSIG)诊断标准,患者凡符合四项标准中的任意一项即归入CNCP组,不论是否合并内脏痛或骨痛。通过标准化访谈收集人口学、肿瘤学及疼痛相关数据,采用绝对标准差及卡方检验或t检验比较组间基线特征差异,并采用Logistic回归分析筛选与CNCP相关的临床因素。结果共纳入138例符合条件的慢性癌性疼痛患者,其中CNCP患者85例(61.6%),非CNCP患者53例(38.4%)。骨转移(adjusted OR=2.316,95% CI:1.074~5.178,P=0.032)、放射治疗史(adjusted OR=2.489,95% CI:1.119~5.803,P=0.025)及排尿异常(adjusted OR=5.470,95% CI:2.150~16.396,P<0.001)与CNCP显著相关。胰腺癌与CNCP呈负相关(OR=0.371,P=0.031)。CNCP患者中,仅5例(3.6%)接受针对神经病理性疼痛的特异性干预,表明当前镇痛治疗仍主要依赖单一模式。结论约三分之二的门诊慢性癌性疼痛患者存在CNCP。骨转移、放射治疗史及排尿异常与CNCP相关,识别这些因素有助于早期发现神经病理性疼痛成分,并采取基于疼痛机制的多模式镇痛管理策略。
“Reporting on the latest research, the study delves into the temporal trends of autism spectrum disorder (ASD) in China from 1990 to 2021, utilizing data from the Global Burden of Disease 2021. The research employs advanced methodologies such as join-point regression, age–period–cohort analysis, and ARIMA modeling to project the future burden of ASD to 2036. The findings reveal a rising ASD burden, significantly influenced by demographic shifts and epidemiological changes, with young children and males being disproportionately affected. This underscores the need for early detection and gender-sensitive interventions.”
李敏, 孟紫妍, 李青, 杨俊涛, 闵开元, 胡志民
2025, 40(4): 282-294. DOI: 10.24920/004535
Abstract:目的探讨1990年至2021年中国孤独症谱系障碍(autism spectrum disorder,ASD)的患病率、发病率和伤残调整寿命年(disability-adjusted life years,DALYs)的时间趋势,并预测至2036年的未来疾病负担。方法数据来源于健康指标与评估研究所(Institute for Health Metrics and Evaluation,IHME)提供的2021年全球疾病负担(Global Burden of Disease,GBD)数据。采用连接点回归估算患病率、发病率和DALYs的年变化百分比(annual percentage change,APC)。采用年龄-时期-队列分析评估年龄、时期和队列的影响。采用分解分析量化人口增长、人口老龄化和流行病学变化的贡献。采用自回归积分滑动平均(AutoRegressive Integrated Moving Average,ARIMA)模型对截至2036年的未来趋势进行预测。结果1990年至2021年间,患病率的平均年变化百分比(average annual percentage changeAAPC)为0.22%(95%不确定区间[UI]:0.20~0.24),发病率为0.07%(95%UI:–0.14~0.28),DALYs为0.23%(95%UI:0.21~0.25)。ASD患病率和DALYs在0~5岁儿童中达到峰值,并在60岁后下降。患病率和DALYs的上升主要归因于人口增长(分别为89.7%和95.2%)和流行病学变化(分别为32.6%和36.2%),而老龄化抵消了增长(分别为–22.4%和–16.0%)。预测结果显示,两性年龄标准化发病率总体保持稳定,但患病率呈现性别差异趋势,男性持续上升而女性有所下降。结论中国ASD负担呈上升趋势,主要受人口学和流行病学因素驱动,其中低龄儿童和男性受影响最为显著。应优先加强早期筛查并实施性别敏感的干预策略。
“In the field of pelvic floor dysfunction, experts systematically review the development stages of PFD-related databases and conduct comparative analysis of international and domestic platforms. The findings provide solutions to strengthen data infrastructure and guide future directions, laying a foundation for the construction of PFD database systems.”
“Reporting on the latest medical advancements, researchers have made significant strides in understanding Adamantinoma-like Ewing sarcoma (ALES), a rare form of cancer. The study, which involved three cases of head and neck ALES, revealed a wide range of histological features and variable immunohistochemical expressions. Notably, it identified a case with a somatic NF1 mutation but without the typical EWSR1 rearrangement, broadening the molecular understanding of ALES. This discovery underscores the diagnostic complexity and the critical need for comprehensive molecular profiling, including next-generation sequencing, to ensure accurate diagnosis and to uncover potential therapeutic targets.”
“In the field of elderly hip arthroplasty nursing, a comprehensive hospital-home-community management model was explored, which provides a replicable framework for the postoperative management of elderly surgical patients.”