MRI Evaluation of Lateral Geniculate Body in Normal Aging Brain Using Quantitative Susceptibility Mapping<sup> △</sup>

Liu Meng-qi; Chen Zhi-ye; Bian Xiang-bing; Liu Meng-yu; Yu Shen-yuan; Ma Lin

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MRI Evaluation of Lateral Geniculate Body in Normal Aging Brain Using Quantitative Susceptibility Mapping^△

中国医学科学杂志（英文版） 2015年30卷第1期页码：34-36

Orginal Article | Updated：2024-04-10

- MRI Evaluation of Lateral Geniculate Body in Normal Aging Brain Using Quantitative Susceptibility Mapping^△
- Affiliations：
  
  Department of Radiology, Chinese People's Liberation Army General Hospital, Beijing 100853, China
- Author bio：
  
  *Corresponding author E-mail: cjr.malin@vip.163.com
- Funds：
  
  △Supported by the National Natural Science Foundation of China (81171319) and Nursery Fund of PLA General Hospital (13KMM41).
- DOI：
  中图分类号：
- 收稿日期：2014-08-26，
  
  网络出版日期：2015-02-20，
  
  纸质出版日期：2015-02
- Accepted：
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MRI Evaluation of Lateral Geniculate Body in Normal Aging Brain Using Quantitative Susceptibility Mapping^△[J]. 中国医学科学杂志（英文版）, 2015,30(1):34-36.

Liu Meng-qi, Chen Zhi-ye, Bian Xiang-bing, et al. MRI Evaluation of Lateral Geniculate Body in Normal Aging Brain Using Quantitative Susceptibility Mapping^△[J]. Chinese medical sciences journal, 2015, 30(1): 34-36.
MRI Evaluation of Lateral Geniculate Body in Normal Aging Brain Using Quantitative Susceptibility Mapping^△[J]. 中国医学科学杂志（英文版）, 2015,30(1):34-36. DOI：

Liu Meng-qi, Chen Zhi-ye, Bian Xiang-bing, et al. MRI Evaluation of Lateral Geniculate Body in Normal Aging Brain Using Quantitative Susceptibility Mapping^△[J]. Chinese medical sciences journal, 2015, 30(1): 34-36. DOI：

摘要

Abstract

Objective

To investigate the changes of lateral geniculate body (LGB) in the normal aging brain using quantitative susceptibility mapping (QSM) technique.

Methods

Magnetic resonance (MR) phase and magnitude images were acquired from enhanced gradient echo T2 star weighted angiography sequence with 16 echoes on 3.0T MR system using the head coil with 32 channels. Morphology Enabled Dipole Inversion (MEDI) method was applied for QSM

and the susceptibility value of LGB was measured by region of interest (ROI) drawn manually on three orthogonal planes.

Results

LGB of the middle-aged group had a higher susceptibility value (0.16±0.05 ppm) than that of the youth group (0.12±0.05 ppm) and elderly group (0.13±0.03 ppm) (all

0.05). Partial correlation analysis demonstrated that there was significantly positive correlation between susceptibility value and age in the youth group (

=0.71

0.05).

Conclusion

LGB could clearly be identified on QSM in the brain

in vivo

关键词

Keywords

references

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Fujita N , Tanaka H , Takanashi M , et al. Lateral geniculate nucleus: Anatomic and functional identification by use of MR imaging. AJNR Am J Neuroradiol 2001 ; 22 : 1719 - 26 .

Li M , He HG , Shi W , et al. Quantification of the human lateral geniculate nucleus in vivo using MR imaging based on morphometry: Volume loss with age. AJNR Am J Neuroradiol 2012 ; 33 : 915 - 21 .

Wang Y , Liu T. Quantitative susceptibility mapping (QSM): Decoding MRI data for a tissue magnetic biomarker. Magn Reson Med 2015 ; 73 : 82 - 101 .

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Greenfield DS , Siatkowski RM , Schatz NJ , et al. Bilateral lateral geniculitis associated with severe diarrhea. Am J Ophthalmol 1996 ; 122 : 280 - 1 .

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