Probiotics’ Preventive Effect on Pediatric Food Allergy: A Meta-analysis of Randomized Controlled Trials

Xiang-yi Kong; Yi Yang; Jian Guan; Ren-zhi Wang

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Probiotics’ Preventive Effect on Pediatric Food Allergy: A Meta-analysis of Randomized Controlled Trials

中国医学科学杂志（英文版） 2014年29卷第3期页码：144-147

• Orginal Article • | Updated：2024-04-10

- Probiotics’ Preventive Effect on Pediatric Food Allergy: A Meta-analysis of Randomized Controlled Trials
- Affiliations：
  
  Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing,China,100730
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 网络出版日期：2014-09-29，
  
  纸质出版日期：2014
- Accepted：
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Xiang-yi Kong, Yi Yang, Jian Guan, 等. Probiotics’ Preventive Effect on Pediatric Food Allergy: A Meta-analysis of Randomized Controlled Trials[J]. 中国医学科学杂志（英文版）, 2014,29(3):144-147.

Xiang-yi Kong, Yi Yang, Jian Guan, et al. Probiotics’ Preventive Effect on Pediatric Food Allergy: A Meta-analysis of Randomized Controlled Trials[J]. Chinese medical sciences journal, 2014, 29(3): 144-147.
Xiang-yi Kong, Yi Yang, Jian Guan, 等. Probiotics’ Preventive Effect on Pediatric Food Allergy: A Meta-analysis of Randomized Controlled Trials[J]. 中国医学科学杂志（英文版）, 2014,29(3):144-147. DOI：

Xiang-yi Kong, Yi Yang, Jian Guan, et al. Probiotics’ Preventive Effect on Pediatric Food Allergy: A Meta-analysis of Randomized Controlled Trials[J]. Chinese medical sciences journal, 2014, 29(3): 144-147. DOI：

摘要

Objective To investigate the preventive effect of probiotics on pediatric food allergy. Methods From MEDLINE bibliographical database

we searched and reviewed all randomized controlled trials on the preventive effects of probiotics on pediatric food allergies up to September 2013 and excluded the studies that do not meet inclusion criteria and extracted the data. Meta-analysis for the results of homogenous studies was performed using RevMan 5.0 and the co-effect was pooled by using fixed-effects model of relative risk (RR) ratios. Results Ten trials published between 2007 and 2012 including 2701 cases were included. Meta-analysis based on included data showed that the preventive effect of prenatal and postnatal probiotic supplementation on food allergies was not significant with the RR=0.88 (95% CI: 0.76-1.03). Conclusion Present evidences cannot show in unequivocal terms that prenatal and postnatal probiotic supplementation will prevent food allergic diseases.

Abstract

Objective To investigate the preventive effect of probiotics on pediatric food allergy. Methods From MEDLINE bibliographical database

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