Objective To explore the diagnosis

classification

and management of uveal effusion syndrome (UES). Methods The clinical data of 10 patients diagnosed with UES in our hospital between 1990-2010 were extracted from hospital records and analyzed

including ophthalmologic examination

ophthalmologic ultrasonography

ultrasound biomicroscopy (UBM)

fundus fluorescence angiography (FFA)

indocyanine green (ICG) angiography

surgical procedures

and outcomes. Results The fundus examination of all impacted eyes showed bullous retinal detachment shifting with head position

confirmed by ultrasonography revealing retinal and choroidal detachment. UBM showed annular peripheral ciliochoroidal detachment in all cases. FFA was performed in 5 patients and revealed leopard spots without leakage from choroid into subretinal space. ICG angiograpy was performed in 3 patients and demonstrated diffused granular marked hyperfluorescence in the choroidal fluorescence in the very early phase

which increased with time and persisted until the late phase. Four eyes of 2 patients underwent full-thickness sclerectomies and 1 eye of 1 patient underwent subscleral sclerectomy

all of whom achieved reattachment of the retina without recurrence during 1-year follow-up. Conclusions Comprehensive preoperative evaluation

including ophthalmologic ultrasonography

computed tomography

and magnetic resonance imaging

is crucial for accurate classification of UES and selection of proper management strategy. Surgical treatment can achieve optimal clinical outcomes for type 1 and type 2 UES.