MITOMYCIN C “STRAIGHT SCLERAL TUNNEL INCISION”-TRABECULECTOMY WITH A RELEASABLE SUTURE
中国医学科学杂志(英文版)2006年0卷第3期 页码:157-162
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MITOMYCIN C “STRAIGHT SCLERAL TUNNEL INCISION”-TRABECULECTOMY WITH A RELEASABLE SUTURE
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中图分类号:R779.6
纸质出版日期:2006
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MITOMYCIN C “STRAIGHT SCLERAL TUNNEL INCISION”-TRABECULECTOMY WITH A RELEASABLE SUTURE[J]. 中国医学科学杂志(英文版), 2006,0(3):157-162.
MITOMYCIN C “STRAIGHT SCLERAL TUNNEL INCISION”- TRABECULECTOMY WITH A RELEASABLE SUTURE[J]. Chinese medical sciences journal, 2006, 0(3): 157-162.
MITOMYCIN C “STRAIGHT SCLERAL TUNNEL INCISION”-TRABECULECTOMY WITH A RELEASABLE SUTURE[J]. 中国医学科学杂志(英文版), 2006,0(3):157-162.DOI:
MITOMYCIN C “STRAIGHT SCLERAL TUNNEL INCISION”- TRABECULECTOMY WITH A RELEASABLE SUTURE[J]. Chinese medical sciences journal, 2006, 0(3): 157-162.DOI:
MITOMYCIN C “STRAIGHT SCLERAL TUNNEL INCISION”-TRABECULECTOMY WITH A RELEASABLE SUTURE
摘要
Abstract
Objective To evaluate the efficacy of “straight scleral tunnel incision”-trabeculectomy with a releasable suture supplemented with mitomycin C (MMC) on reducing intraocular pressure (IOP)
complications
and corneal astigmatism in patients with primary angle-closure glaucoma (PACG). Methods Totally 217 acute or chronic PACG patients with occludable angle above 180° and IOP above 21mmHg were divided into 3 groups. Patients in group A (98 cases
128 eyes)
B (71 cases
95 eyes)
and C (48 cases
60 eyes) were treated with “straight scleral tunnel incision”-trabeculectomy with a releasable suture supplemented with MMC
releasable suture trabeculectomy with MMC
and trabeculectomy with MMC
respectively. IOP
complications
and surgically induced astigmatism (SIA) were evaluated preoperatively and up to 12 months postoperatively. [JP+2]Results IOP of 2 weeks after treatment was significantly lower than preoperative IOP in all the 3 groups (all P<0.001). Success rates (IOP≤20 mmHg) in group A
B
and C were 87.91%
89.23%
and 83.72% respectively at 12 months after treatment (P=0.256). The incidence of shallow anterior chamber and hypotony had no significant difference between group A and B
but both of them were lower than that in group C (P<0.05). There were no significant differences in preoperative corneal astigmatism among the 3 groups. The corneal astigmatism after 2 weeks in group A (1.71±1.47D) was higher than that before operation (1.28±1.05D
P=0.126). With 12 months gone
the astigmatism almost returned to preoperative levels. The corneal astigmatisms after 2 weeks in group B and C (1.99±1.20D and 2.22±1.39D) were significantly higher than those before operation (1.20±0.85D and 1.18±0.93D
P=0.002
P=0.001)
respectively. With 12 months gone
the mean astigmatisms in group B and C (1.87±0.91D and 1.90±1.16D) were still significantly higher than those before operation ( P=0.001
P=0.003). The highest astigmatic polar values in group A
B
and C (1.00D
1.89D
and 1.77D) occurred after 2 weeks
1 month
and 1 month postoperation
respectively
which were significantly higher than those before operation (0.19±1.32D
0.12±1.22D
and 0.17±1.25D
P<0.01)
respectively. With 12 months gone
they were 0.03D
-0.18D
and -0.13D higher than those before operation
respectively. The rates of function bleb and thin-wall bleb were 71.43% and 26.37% in group A
75.38% and 29.23% in group B
72.09% and 25.58% in group C
respectively at 12 months after treatment. There were no significant differences among the 3 groups.