Objective To evaluate the feasibility and safety of operative laparoscopy for ectopic pregnancy with hypovolemic shock. Methods Two hundred and fifteen women with ectopic pregnancy underwent operative laparoscopy. These patients were divided into two groups. The study group included 21 patients with shock and intraperitoneal hemorrhage more than 1000 mL

and control group included 194 patients

hemodynamically stable

with blood loss less than 1000 mL. Clinical data of perio-perative periods in two groups were retrospectively analyzed. Results All patients were tubal pregnancies. The occurrence rate of tubal rupture was higher in study group than in control group （80.95% vs. 15.98%

P < 0.001）. Intraabdominal blood loss was significantly higher in study group than in control group （1900 mL vs. 300 mL

P < 0.001）

and autologous blood transfusions were given to 95.24% and 9.3% of patients in study and control group

respectively （P < 0.001）. Laparoscopic salpingectomy was performed on 85.7 % and 50.5% of patients in study and control group （P < 0.001）. The operative time was somewhat longer in study group than that in control group （60 minutes vs. 45 minutes）

but with no significant difference. All patients had no perioperative complications. Conclusion Operative laparoscopy in patients with hopovolemic shock can be safely and effectively performed by experi-enced laparoscopists with the aid of optimal anesthesia

advanced cardiovascular monitoring

and autologous blood transfusion.