Objective. To explore the correlations between the occurrence and severity of neglect and the region

range or extent of the decrease in regional cerebral blood flow （rCBF）.Methods. Nineteen dextromanual patients who were diagnosed as unilateral stroke clinically and hemispa-tial neglect by a neglect test battery received single photon emission computed tomography （SPECT） scans.Results. On images

the damages of patients with neglect were seen most frequently in the frontal cortex

and then in turn in the parietal cortex

occipital cortex

temporal cortex

basal ganglia and thalamus. Most patients with neglect had two or more regions damaged. The most significant region was temporal - parietal - occipital （TPO） junction. The correlation coefficient between rCBF and the severity of neglect was - 0. 34 （t = -1.5

P> 0. 05）

and that between the decrease percentage of rCBF and the severity of neglect was 0. 34 （t = 1. 47

P> 0. 05）. The correlation coefficients between the range

number of foci

the flow deficit size and the severity of neglect were 0. 71 （t=4. 13

P <0. 01）

0. 70 （t=4. 07

P <0. 01） and 0. 64 （t = 3. 40

P <0. 01）

respectively.Conclusions. The severity of neglect correlates with rCBF and the decrease percentage of rCBF insignificantly

but correlates positively with the range

number of foci and the flow deficit size significantly. Hemispatial neglect is caused by the damage of multiple sites and combined damage results in more severe neglect.