EFFECT  OF  COXSACKIEVIRUS  B3  ON  ION  CHANNEL  CURRENTS  IN  RAT  VENTRICULAR  MYOCYTES

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EFFECT OF COXSACKIEVIRUS B3 ON ION CHANNEL CURRENTS IN RAT VENTRICULAR MYOCYTES

中国医学科学杂志（英文版） 2000年0卷第3期页码：150-153

Updated：2024-04-10

- EFFECT OF COXSACKIEVIRUS B3 ON ION CHANNEL CURRENTS IN RAT VENTRICULAR MYOCYTES
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  中图分类号： R373.23
- 纸质出版日期：2000
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EFFECT OF COXSACKIEVIRUS B3 ON ION CHANNEL CURRENTS IN RAT VENTRICULAR MYOCYTES[J]. 中国医学科学杂志（英文版）, 2000,0(3):150-153.

EFFECT OF COXSACKIEVIRUS B3 ON ION CHANNEL CURRENTS IN RAT VENTRICULAR MYOCYTES[J]. Chinese medical sciences journal, 2000, 0(3): 150-153.
EFFECT OF COXSACKIEVIRUS B3 ON ION CHANNEL CURRENTS IN RAT VENTRICULAR MYOCYTES[J]. 中国医学科学杂志（英文版）, 2000,0(3):150-153. DOI：

EFFECT OF COXSACKIEVIRUS B3 ON ION CHANNEL CURRENTS IN RAT VENTRICULAR MYOCYTES[J]. Chinese medical sciences journal, 2000, 0(3): 150-153. DOI：

摘要

Abstract

To investigate the effects of coxsackievirus B 3（CVB 3） on ion channel currents in rat ventricular myocytes. Methods.Rat hearts were isolated with collagenase to acquire single ventricular myocytes

L type voltage dependent calcium channel（VDCC）current （I Ca ）

Na + current （I Na ）

outward potassium current （I out ）

inwardly rectifying potassium current（I KI ） were recorded using whole cell patch clamp techniques. ResultsCVB 3 infection increased I Ca and I out

while decreased I KI ; but it had no obvious effect on I Na . Conclusion.The effects of CVB 3 on I Ca 、 I out 、 I KI may be one of the mechanisms of myocytes damage and the occurrence of abnormal electroactivities induced by CVB 3 infection.

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