Objective’ Recent studies indicated that incidence of occlusive cardiovascular diseases increased in psoriasis. Changes of serum lipid metabolism may be the cause. Apolipoproteinsplay a central role in lipoprotein metabolism in serum. The measurement of serum apo levelsmay reveal the characteristics of lipoprotein metabolism in serum in patients with psoriasisand may help to find an answer to the cause of the high incidence of occlusive cardiovasculardiseases in psoriasis.Method. The apo levels of 31 patients with psoriasis vulgaris and 31 sex- and age-matched healthy individuals with normal serum lipid levels were measured by radial immuno-diffusion assay.Results’ The apo C Ⅲ （t= 2.44

P<0. 05） and apo E （t=2. 12

P<0. 05） of psoriat-ic group elevated significantly- The apo C Ⅲ（t= 2.77

P<0.01） of patients less than 40-year-old and apoE （t= 2. 91

P<0. 01） of male patients eIevated significantly. Conclusha. Abndrmal metabolism of lipoprotein in serum exist in psoriasis

especially inmale patients and/or patients less than 40 years old.