A　COMPLEX　OF　INTERMEDIATE　FILAMENT　PROTEIN－DNA：A　TARGET　FOR　AUTOANTIBODIES　IN　SYSTEMIC　LUPUS　ERYTHEMATOSUS？

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A　COMPLEX　OF　INTERMEDIATE　FILAMENT　PROTEIN－DNA：A　TARGET　FOR　AUTOANTIBODIES　IN　SYSTEMIC　LUPUS　ERYTHEMATOSUS？

中国医学科学杂志（英文版） 1995年第2期

Updated：2024-04-10

- A　COMPLEX　OF　INTERMEDIATE　FILAMENT　PROTEIN－DNA：A　TARGET　FOR　AUTOANTIBODIES　IN　SYSTEMIC　LUPUS　ERYTHEMATOSUS？
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  中图分类号： R363
- 纸质出版日期：1995
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[1]阎锡蕴.A　COMPLEX　OF　INTERMEDIATE　FILAMENT　PROTEIN－DNA：A　TARGET　FOR　AUTOANTIBODIES　IN　SYSTEMIC　LUPUS　ERYTHEMATOSUS？[J].Chinese Medical Sciences Journal,1995(02):90-92.

A COMPLEX OF INTERMEDIATE FILAMENT PROTEIN-DNA:A TARGET FOR AUTOANTIBODIES IN SYSTEMIC LUPUS ERYTHEMATOSUS?[J]. Chinese medical sciences journal, 1995, (2).
[1]阎锡蕴.A　COMPLEX　OF　INTERMEDIATE　FILAMENT　PROTEIN－DNA：A　TARGET　FOR　AUTOANTIBODIES　IN　SYSTEMIC　LUPUS　ERYTHEMATOSUS？[J].Chinese Medical Sciences Journal,1995(02):90-92. DOI：

A COMPLEX OF INTERMEDIATE FILAMENT PROTEIN-DNA:A TARGET FOR AUTOANTIBODIES IN SYSTEMIC LUPUS ERYTHEMATOSUS?[J]. Chinese medical sciences journal, 1995, (2). DOI：

摘要

ＡＣＯＭＰＬＥＸＯＦＩＮＴＥＲＭＥＤＩＡＴＥＦＩＬＡＭＥＮＴＰＲＯＴＥＩＮ－ＤＮＡ：ＡＴＡＲＧＥＴＦＯＲＡＵＴＯＡＮＴＩＢＯＤＩＥＳＩＮＳＹＳＴＥＭＩＣ　ＬＵＰＵＳＥＲＹＴＨＥＭＡＴＯＳＵＳ？ＹａｎＸｉｙｕｎ（阎锡蕴）；Ｓ．ＫｕｈｎａｎｄＰ．Ｔｒａｕ...

Abstract

Autoantibodies in systemic lupus erythematosus which cross-react with double stranded DNA and intermediate filament proteins are frequently reported. However

little is Known about the origin and the target of these antibodies. In this paper

a polyspecific monoclonal antibody

XY12

produced by the immunization of genetically non-autoimmune mice with a DNA-protein complex is detailed. Its antigen binding patterns are very similar to the autoantibodies. The data suggest that these autoantibedies may be triggered by a circulating nucleoprotein.

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