In this paper the results of skeletal traction and irrigation therapy （STIT） used for open fracture complicated with large-sized full-thickness skin-deficit and infection wounds （OFIW） were presented. Fourteen patients of OFIW were treated by the plaster cast and wound dressing （PCWD）

and 30 patients of OFIW were treated by STIT. The results indicated that after one week of treatment

the white blood cell count in the STIT group

compared to 17. 6±l. 0×109/L from before treatment

returned to 8. 8±0. 8×109/L

and in contrast

the cell count of the PCWD group was about 13. 0±1. 4×109/L. All of wound exudate culture in the STIT group was negative

and those of 7 cases （7/14） in PCWD group were positive （P<0. 0l）. The symptoms and signs such as pain

fever and septic exudate on the wound in the STIT group were much milder than those in the PCWD group. There were 5 cases （35. 7%） of toxicemia and septicemia

2 cases （14. 3%） of osteomyelitis

2 cases （14. 3 %） of amputation

1 case （7. 1%） of delayed union and 3 cases （21. 4 %） of malunion in the PCWD group

and no complications in the STIT group.