STUDY ON INHIBITION OF PANCREATIC EXOCRINE SECRETION BY SOMATOSTATIN IN RATS

何晓东

Your Location：

Home >

Browse articles >

STUDY ON INHIBITION OF PANCREATIC EXOCRINE SECRETION BY SOMATOSTATIN IN RATS

中国医学科学杂志（英文版） 1996年第3期

Updated：2024-04-10

- STUDY ON INHIBITION OF PANCREATIC EXOCRINE SECRETION BY SOMATOSTATIN IN RATS
- Affiliations：
- Author bio：
- Funds：
- DOI：
  中图分类号： R335
- 纸质出版日期：1996
- Accepted：
Scan QR Code
[1]何晓东.STUDY ON INHIBITION OF PANCREATIC EXOCRINE SECRETION BY SOMATOSTATIN IN RATS[J].Chinese Medical Sciences Journal,1996(03):166-169.

STUDY ON INHIBITION OF PANCREATIC EXOCRINE SECRETION BY SOMATOSTATIN IN RATS[J]. Chinese medical sciences journal, 1996, (3).
[1]何晓东.STUDY ON INHIBITION OF PANCREATIC EXOCRINE SECRETION BY SOMATOSTATIN IN RATS[J].Chinese Medical Sciences Journal,1996(03):166-169. DOI：

STUDY ON INHIBITION OF PANCREATIC EXOCRINE SECRETION BY SOMATOSTATIN IN RATS[J]. Chinese medical sciences journal, 1996, (3). DOI：

摘要

ＳＴＵＤＹＯＮＩＮＨＩＢＩＴＩＯＮＯＦＰＡＮＣＲＥＡＴＩＣＥＸＯＣＲＩＮＥＳＥＣＲＥＴＩＯＮＢＹＳＯＭＡＴＯＳＴＡＴＩＮＩＮＲＡＴＳ￥ＨｅＸｉａｏｄｏｎｇ；（何晓东）Ｍ．Ｔ．ＮｅｌｓｏｎａｎｄＨ．Ｄｅｂａｓ(ＧａｓｔｒｏｉｎｔｅｓｔｉｎａｌＲｅｓｅａ...

Abstract

We used a potent and specific monoclonal antibody to somatostatin to test the physiologic inhibitory role of the tetradecapeptide somatostatin on pancreatic secretion.Somatostatin immunoneutralization increased both the total amylase and volume of pancreatic secretion.Cholecystokinin-A receptor antagonism abolished the stimulatory effect of somatostatin immunoneutralization.We conclude that somatostatin tonically inhibits pancreatic secretion in fasted rats via inhibition of the release or action of cholecystokinin.Furthermore

the source of these peptides is likely islet delta cells and intrapancreatic neurons

respectively.

关键词

Keywords

references

浏览量

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

关联资源

暂无数据