The aim of this study was to detect coronary artery disease using 99m Tc MIBI myocardial perfusion imaging in patients with valvular disease. [WT5”BX]Methods.[WT5”BZ] Thirty patients with valvular disease confirmed by echocardiography underwent 99m Tc MIBI myocardial perfusion imaging using multiSPECT 1h after stress test （exercise

dipyridamole or dobutamine test） and were performed coronary angiography within 1 month before valvular operation. [WT5”BX]Results.[WT5”BZ]For 29 out of the 30 patients

the results of 99m Tc MIBI myocardial perfusion imaging were similar with those of coronary angiography

the concordance rate was 96 7% and the negative predictability was 100%. [WT5”BX]Conclusion.[WT5”BZ] 99m Tc MIBI myocardial perfusion imaging is a reliable non invasive method for detecting coronary artery disease in patients with valvular disease and so as to draw up suitable operation programs for them.