EXPRESSION OF BONE MORPHOGENETIC PROTEIN-1 IN FETAL HUMAN CARTILAGE AND BONE DURING ENDOCHONDRAL OSSIFICATION

Your Location：

Home >

Browse articles >

EXPRESSION OF BONE MORPHOGENETIC PROTEIN-1 IN FETAL HUMAN CARTILAGE AND BONE DURING ENDOCHONDRAL OSSIFICATION

中国医学科学杂志（英文版） 1998年0卷第3期页码：129-133

Updated：2024-04-10

- EXPRESSION OF BONE MORPHOGENETIC PROTEIN-1 IN FETAL HUMAN CARTILAGE AND BONE DURING ENDOCHONDRAL OSSIFICATION
- Affiliations：
- Author bio：
- Funds：
  
  National Natural Science Foundation of China
- DOI：
  中图分类号： R681.3
- 纸质出版日期：1998
- Accepted：
Scan QR Code
EXPRESSION OF BONE MORPHOGENETIC PROTEIN-1 IN FETAL HUMAN CARTILAGE AND BONE DURING ENDOCHONDRAL OSSIFICATION[J]. 中国医学科学杂志（英文版）, 1998,0(3):129-133.

EXPRESSION OF BONE MORPHOGENETIC PROTEIN-1 IN FETAL HUMAN CARTILAGE AND BONE DURING ENDOCHONDRAL OSSIFICATION[J]. Chinese medical sciences journal, 1998, 0(3): 129-133.
EXPRESSION OF BONE MORPHOGENETIC PROTEIN-1 IN FETAL HUMAN CARTILAGE AND BONE DURING ENDOCHONDRAL OSSIFICATION[J]. 中国医学科学杂志（英文版）, 1998,0(3):129-133. DOI：

EXPRESSION OF BONE MORPHOGENETIC PROTEIN-1 IN FETAL HUMAN CARTILAGE AND BONE DURING ENDOCHONDRAL OSSIFICATION[J]. Chinese medical sciences journal, 1998, 0(3): 129-133. DOI：

摘要

Abstract

The expression of mRNA for bone morphogenetic protein-1 （BMP-1） was investigated in fetal human cartilage and bone during the developing endochondral ossification by using in situ hybridization. BMP-1 mRNA was localized in the hypertrophic chondrocytes

the cells of perichondrium

osteoblasts and marrow cells. The results suggest that BMP-1 may involve in cartilage and bone formation

and in regulation of calcification of growth plate.As a comparative study

the expression of TGF-β1 protein was investigated in cartilage and bone using immunohistochemical staining

correlated expression of TGF-β1 and BMP-1 was found. The results suggest that BMP-1 and TGF-β1 act synergistically to influence endochrondral ossification.

关键词

Keywords

references

浏览量

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

关联资源

CARTILAGE- LIKE PHENOMENON IN THE ANTERIOR CRUCIATE LIGAMENT