TREATMENT OF PATIENTS WITH MALIGNANT PLEURAL EFFUSIONS DUE TO ADVANCED LUNG CANCER BY TRANSFER OF AUTOLOGOUS LAK CELLS COMBINED WITH rIL-2 OR rIL-2 ALONE

李殿俊; 王跃荣; 姚晓东; 邵杰; 陈云富; 巴德年

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TREATMENT OF PATIENTS WITH MALIGNANT PLEURAL EFFUSIONS DUE TO ADVANCED LUNG CANCER BY TRANSFER OF AUTOLOGOUS LAK CELLS COMBINED WITH rIL-2 OR rIL-2 ALONE

中国医学科学杂志（英文版） 1990年第1期页码：51-55

Updated：2024-04-10

- TREATMENT OF PATIENTS WITH MALIGNANT PLEURAL EFFUSIONS DUE TO ADVANCED LUNG CANCER BY TRANSFER OF AUTOLOGOUS LAK CELLS COMBINED WITH rIL-2 OR rIL-2 ALONE
- Affiliations：
  
  1. Heilongjiang Branch CAMS
  2. ,China
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版日期：1990
- Accepted：
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[1]李殿俊,王跃荣,姚晓东,邵杰,陈云富,巴德年.TREATMENT OF PATIENTS WITH MALIGNANT PLEURAL EFFUSIONS DUE TO ADVANCED LUNG CANCER BY TRANSFER OF AUTOLOGOUS LAK CELLS COMBINED WITH rIL-2 OR rIL-2 ALONE[J].Chinese Medical Sciences Journal,1990(01):51-55.

TREATMENT OF PATIENTS WITH MALIGNANT PLEURAL EFFUSIONS DUE TO ADVANCED LUNG CANCER BY TRANSFER OF AUTOLOGOUS LAK CELLS COMBINED WITH rIL-2 OR rIL-2 ALONE[J]. Chinese medical sciences journal, 1990, (1): 51-55.
[1]李殿俊,王跃荣,姚晓东,邵杰,陈云富,巴德年.TREATMENT OF PATIENTS WITH MALIGNANT PLEURAL EFFUSIONS DUE TO ADVANCED LUNG CANCER BY TRANSFER OF AUTOLOGOUS LAK CELLS COMBINED WITH rIL-2 OR rIL-2 ALONE[J].Chinese Medical Sciences Journal,1990(01):51-55. DOI：

TREATMENT OF PATIENTS WITH MALIGNANT PLEURAL EFFUSIONS DUE TO ADVANCED LUNG CANCER BY TRANSFER OF AUTOLOGOUS LAK CELLS COMBINED WITH rIL-2 OR rIL-2 ALONE[J]. Chinese medical sciences journal, 1990, (1): 51-55. DOI：

摘要

<正> Experimental study both in vitro and in vivotogether with clinical trials showed that LAKcells have antitumor and antimetastatic effects（1-5）and that these effects are closely related tothe number of LAK cells transferred and the ad-ministration of rIL-2（1

6-8）.Usually

autologousPBL’s are used as the source of LAK precursorsin the adoptive immunotherapy of cancer patients.But this not only puts an added burden on thecancer patient

it can cause serious side effectsas well（9）.Although TIL’s may provide a solu-tion to this problem（10

11）

their isolation fromsolid tumors is complex and consumes many rea-gents.We have reported that the isolation oflymphocytes from malignant ascites or from ma-lignant pleural effusions is not only simple and

Abstract

6-8）.Usually

autologousPBL’s are used as the source of LAK precursorsin the adoptive immunotherapy of cancer patients.But this not only puts an added burden on thecancer patient

it can cause serious side effectsas well（9）.Although TIL’s may provide a solu-tion to this problem（10

11）

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