ABNORMAL　LEFT　VENTRICULAR　SYSTOLIC　AND　DIASTOLIC　FUNCTIONAL　RESPONSE　TO　ISOMETRIC　EXERCISE　IN　IDIOPATHIC　DILATED　CARDIOMYOPAT

沈卫峰; 张宪; 胡厚达; 龚兰生

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ABNORMAL　LEFT　VENTRICULAR　SYSTOLIC　AND　DIASTOLIC　FUNCTIONAL　RESPONSE　TO　ISOMETRIC　EXERCISE　IN　IDIOPATHIC　DILATED　CARDIOMYOPAT

中国医学科学杂志（英文版） 1995年第4期

Updated：2024-04-10

- ABNORMAL　LEFT　VENTRICULAR　SYSTOLIC　AND　DIASTOLIC　FUNCTIONAL　RESPONSE　TO　ISOMETRIC　EXERCISE　IN　IDIOPATHIC　DILATED　CARDIOMYOPAT
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  中图分类号： R363
- 纸质出版日期：1995
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[1]沈卫峰,张宪,胡厚达,龚兰生.ABNORMAL　LEFT　VENTRICULAR　SYSTOLIC　AND　DIASTOLIC　FUNCTIONAL　RESPONSE　TO　ISOMETRIC　EXERCISE　IN　IDIOPATHIC　DILATED　CARDIOMYOPAT[J].Chinese Medical Sciences Journal,1995(04):232-236.

Shen Weifeng, Zhang Xian, Hu Heda and Gong Lansheng. ABNORMAL LEFT VENTRICULAR SYSTOLIC AND DIASTOLIC FUNCTIONAL RESPONSE TO ISOMETRIC EXERCISE IN IDIOPATHIC DILATED CARDIOMY-OPATHY: BENEFICIAL EFFECT OF CAPTOPRIL[J]. Chinese medical sciences journal, 1995, (4).
[1]沈卫峰,张宪,胡厚达,龚兰生.ABNORMAL　LEFT　VENTRICULAR　SYSTOLIC　AND　DIASTOLIC　FUNCTIONAL　RESPONSE　TO　ISOMETRIC　EXERCISE　IN　IDIOPATHIC　DILATED　CARDIOMYOPAT[J].Chinese Medical Sciences Journal,1995(04):232-236. DOI：

Shen Weifeng, Zhang Xian, Hu Heda and Gong Lansheng. ABNORMAL LEFT VENTRICULAR SYSTOLIC AND DIASTOLIC FUNCTIONAL RESPONSE TO ISOMETRIC EXERCISE IN IDIOPATHIC DILATED CARDIOMY-OPATHY: BENEFICIAL EFFECT OF CAPTOPRIL[J]. Chinese medical sciences journal, 1995, (4). DOI：

摘要

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Abstract

In 19 patients with idiopathic dilated cardiomyopathy and symptoms of congetive heart failure

left ventricular （LV） systolic performance and diastolic velocity profiles were assessed by two- dimensional echocardiography and pulsed wave Doppler at rest and during handgrip exercise before and ninety minutes after administration of captopril （mean dose 25 +12mg; range 12. 5─50mg）. Although heart rate and blood pressure increased similarly during handgrip exercise before and after captopril treatment

both were lower with handgrip exercise during captopril treatment. The results from this study indicated that acute angiotensin converting enzyme inhibition with captopril reduces preload and afterload and ameliorates handgrip exercise-induced LV systolic and diastolic filling dysfunction in patients with congestive heart failure secondary to idiopathic dilated cardiomyopathy.

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