
FOLLOWUS
1. Central Laboratory, The Second Hospital of Jiaxing City, Jiaxing, Zhejiang 314000, China
2. Department of Oncology, The Second Hospital of Jiaxing City, Jiaxing, Zhejiang 314000, China
*E-mail: ybao2011@gmail.com; Tel: 86-0573-82073185.
收稿日期:2018-08-28,
录用日期:2018-10-22,
网络出版日期:2019-12-06,
纸质出版日期:2019-12-06
Scan QR Code
鲍轶, 莫娟芬, 吴加元, 等. 非小细胞肺癌患者外周血CD8+和γδT细胞亚群表面PD1和BTLA的表达[J]. 中国医学科学杂志(英文版), 2019,34(4):248-255.
Bao Yi, Mo Juanfen, Wu Jiayuan, et al. Expression of PD1 and BTLA on the CD8+ T Cell and γδT Cell Subsets in Peripheral Blood of Non-Small Cell Lung Cancer Patients[J]. Chinese medical sciences journal, 2019, 34(4): 248-255.
鲍轶, 莫娟芬, 吴加元, 等. 非小细胞肺癌患者外周血CD8+和γδT细胞亚群表面PD1和BTLA的表达[J]. 中国医学科学杂志(英文版), 2019,34(4):248-255. DOI: 10.24920/003498.
Bao Yi, Mo Juanfen, Wu Jiayuan, et al. Expression of PD1 and BTLA on the CD8+ T Cell and γδT Cell Subsets in Peripheral Blood of Non-Small Cell Lung Cancer Patients[J]. Chinese medical sciences journal, 2019, 34(4): 248-255. DOI: 10.24920/003498.
Bray F , Ferlay J , Soerjomataram I , et al . Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries . CA Cancer J Clin 2018 ; 68 ( 6 ): 394 - 424 . doi: 10.3322/caac.21492 1001-9294-34-4-248/caac.21492 .
Moon EK , Langer CJ , Albelda SM . The era of checkpoint blockade in lung cancer: taking the brakes off the immune system . Ann Am Thorac Soc 2017 ; 14 ( 8 ): 1248 - 60 . doi: 10.1513/AnnalsATS.201702-152FR 1001-9294-34-4-248/AnnalsATS.201702-152FR .
Cruz MS , Diamond A , Russell A , et al . Human alphabeta and gammadelta T cells in skin immunity and disease . Front Immunol 2018 ; 9 : 1304 . doi: 10.3389/fimmu.2018.01304 1001-9294-34-4-248/fimmu.2018.01304 .
Chien YH , Meyer C , Bonneville M . Gammadelta T cells: first line of defense and beyond . Annu Rev Immunol 2014 ; 32 : 121 - 55 . doi: 10.1146/annurev-immunol-032713-120216 1001-9294-34-4-248/annurev-immunol-032713-120216 .
Urban EM , Chapoval AI , Pauza CD . Repertoire development and the control of cytotoxic/effector function in human gammadelta T cells . Clin Dev Immunol 2010 ; 2010 : 732893 . doi: 10.1155/2010/732893 1001-9294-34-4-248/2010/732893 .
Rudd CE , Taylor A , Schneider H . CD28 and CTLA-4 coreceptor expression and signal transduction . Immunol Rev 2009 ; 229 ( 1 ): 12 - 26 . doi: 10.1111/j.1600-065X.2009.00770.x 1001-9294-34-4-248/j.1600-065X.2009.00770.x .
Chikuma S . CTLA-4, an essential immune-checkpoint for T-cell activation . Curr Top Microbiol Immunol 2017 ; 410 : 99 - 126 . doi: 10.1007/82_2017_61 1001-9294-34-4-248/82_2017_61 .
Chen L , Flies DB . Molecular mechanisms of T cell co-stimulation and co-inhibition . Nat Rev Immunol 2013 ; 13 ( 4 ): 227 - 42 . doi: 10.1038/nri3405 1001-9294-34-4-248/nri3405 .
Edge SB , Compton CC . The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM . Ann Surg Oncol 2010 ; 17 ( 6 ): 1471 - 4 . doi: 10.3322/caac.21388 1001-9294-34-4-248/caac.21388 .
Chen L . Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity . Nat Rev Immunol 2004 ; 4 ( 5 ): 336 - 47 . doi: 10.1038/nri1349 1001-9294-34-4-248/nri1349 .
Riley JL . PD-1 signaling in primary T cells . Immunol Rev 2009 ; 229 ( 1 ): 114 - 25 . doi: 10.1111/j.1600-065X.2009.00767.x 1001-9294-34-4-248/j.1600-065X.2009.00767.x .
Kulpa DA , Lawani M , Cooper A , et al . PD-1 coinhibitory signals: the link between pathogenesis and protection . Semin Immunol 2013 ; 25 ( 3 ): 219 - 27 . doi: 10.1016/j.smim.2013.02.002 1001-9294-34-4-248/j.smim.2013.02.002 .
Hall RD , Gray JE , Chiappori AA . Beyond the standard of care: a review of novel immunotherapy trials for the treatment of lung cancer . Cancer Control 2013 ; 20 ( 1 ): 22 - 31 . doi: 10.1177/107327481302000105 1001-9294-34-4-248/107327481302000105 .
Pasero C , Speiser DE , Derre L , et al . The HVEM network: new directions in targeting novel costimulatory/co-inhibitory molecules for cancer therapy . Curr Opin Pharmacol 2012 ; 12 ( 4 ): 478 - 85 . doi: 10.1016/j.coph.2012.03.001 1001-9294-34-4-248/j.coph.2012.03.001 .
Wherry EJ , Kurachi M . Molecular and cellular insights into T cell exhaustion . Nat Rev Immunol 2015 ; 15 ( 8 ): 486 - 99 . doi: 10.1038/nri3862 1001-9294-34-4-248/nri3862 .
Gertner-Dardenne J , Fauriat C , Orlanducci F , et al . The co-receptor BTLA negatively regulates human Vgamma9Vdelta2 T-cell proliferation: a potential way of immune escape for lymphoma cells . Blood 2013 ; 122 ( 6 ): 922 - 31 . doi: 10.1182/blood-2012-11-464685 1001-9294-34-4-248/blood-2012-11-464685 .
Watanabe N , Gavrieli M , Sedy JR , et al . BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1 . Nat Immunol 2003 ; 4 ( 7 ): 670 - 9 . doi: 10.1038/ni944 1001-9294-34-4-248/ni944 .
Pasero C , Olive D . Interfering with coinhibitory molecules: BTLA/HVEM as new targets to enhance anti-tumor immunity . Immunol Lett 2013 ; 151 ( 1-2 ): 71 - 5 . doi: 10.1016/j.imlet.2013.01.008 1001-9294-34-4-248/j.imlet.2013.01.008 .
Ware CF , Sedy JR . TNF superfamily networks: bidirectional and interference pathways of the herpesvirus entry mediator (TNFSF14) . Curr Opin Immunol 2011 ; 23 ( 5 ): 627 - 31 . doi: 10.1016/j.coi.2011.08.008 1001-9294-34-4-248/j.coi.2011.08.008 .
Radvanyi LG , Bernatchez C , Zhang M , et al . Specific lymphocyte subsets predict response to adoptive cell therapy using expanded autologous tumor-infiltrating lymphocytes in metastatic melanoma patients . Clin Cancer Res 2012 ; 18 ( 24 ): 6758 - 70 . doi: 10.1158/1078-0432.CCR-12-1177 1001-9294-34-4-248/1078-0432.CCR-12-1177 .
Lou Y , Diao L , Cuentas ER , et al . Epithelial-mesenchymal transition is associated with a distinct tumor microenvironment including elevation of inflammatory signals and multiple immune checkpoints in lung adenocarcinoma . Clin Cancer Res 2016 ; 22 ( 14 ): 3630 - 42 . doi: 10.1158/1078-0432.CCR-15-1434 1001-9294-34-4-248/1078-0432.CCR-15-1434 .
Beetz S , Wesch D , Marischen L , et al: Innate immune functions of human gammadelta T cells . Immunobiology 2008 ; 213 ( 3-4 ): 173 - 82 . doi: 10.1016/j.imbio.2007.10.006 1001-9294-34-4-248/j.imbio.2007.10.006 .
Marten A , Lilienfeld-Toal M , Buchler MW , et al . Zoledronic acid has direct antiproliferative and antimetastatic effect on pancreatic carcinoma cells and acts as an antigen for delta2 gamma/delta T cells . J Immunother 2007 ; 30 ( 4 ): 370 - 7 . doi: 10.1097/CJI.0b013e31802bff16 1001-9294-34-4-248/CJI.0b013e31802bff16 .
Lipton A , Cook RJ , Major P , et al . Zoledronic acid and survival in breast cancer patients with bone metastases and elevated markers of osteoclast activity . Oncologist 2007 ; 12 ( 9 ): 1035 - 43 . doi: 10.1634/theoncologist.12-9-1035 1001-9294-34-4-248/theoncologist.12-9-1035 .
关联资源
相关文章
相关作者
相关机构
京公网安备11010802024621