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视神经脊髓炎谱系疾病合并疼痛抑郁共病综述
- Affiliations：
1. 1Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
2. 2Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
- Author bio：
*Tel: 86-18612672127, E-mail: hazelbeijing@vip.163.com
- Funds：Fundamental Research Funds for the Central Universities(3332021015)
DOI：10.24920/003859
中图分类号：收稿日期：2020-11-30，
网络出版日期：2021-11-08，
纸质出版日期：2021-12-31
- Accepted：
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张雪, 徐雁, 裴丽坚. 视神经脊髓炎谱系疾病合并疼痛抑郁共病综述[J]. 中国医学科学杂志（英文版）, 2021,36(4):316-322.
Zhang Xue, Xu Yan, Pei Lijian. Review of Neuromyelitis Optica Spectrum Disorder with Pain-Depression Comorbidity[J]. Chinese medical sciences journal, 2021, 36(4): 316-322.
张雪, 徐雁, 裴丽坚. 视神经脊髓炎谱系疾病合并疼痛抑郁共病综述[J]. 中国医学科学杂志（英文版）, 2021,36(4):316-322. DOI： 10.24920/003859.
Zhang Xue, Xu Yan, Pei Lijian. Review of Neuromyelitis Optica Spectrum Disorder with Pain-Depression Comorbidity[J]. Chinese medical sciences journal, 2021, 36(4): 316-322. DOI： 10.24920/003859.
摘要
视神经脊髓炎谱系疾病是一种中枢神经系统炎性疾病
主要累及视神经及脊髓
在亚洲人群中发病率显著高于世界其他地区。80%以上视神经脊髓炎谱系疾病患者合并疼痛症状
其中痛性痉挛及神经病理性疼痛最具特点。抑郁常与疼痛共存
严重影响患者生活质量。近年来
很多研究发现疼痛与抑郁在机制上存在重叠
然而两者之间的联系仍不明确。本文对视神经脊髓炎谱系疾病患者合并疼痛抑郁共病的流行病学特征、发病机制及诊断治疗进行综述。
Abstract
Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disorder of the central nervous system predominantly targeting optic nerves and the spinal cord. The prevalence of the disease is much higher in Asia than in other parts of the world. Pain can be detected in more than 80% of NMOSD patients
with evoked pain mostly being caused by painful tonic muscle spasms and neuropathic pain as the most characteristic types. Depression is often comorbid with pain
and their comorbidity can severely influence quality of life. In recent years
studies have found considerable overlaps between the mechanisms of pain and depression; however
their association remains unclear. This article reviews the epidemiology
mechanism
evaluation and treatment of pain-depression comorbidity in NMOSD patients.
关键词
Keywords
references
Cabrera-Gómez JA , Kurtzke JF , González-Quevedo A , et al . An epidemiological study of neuromyelitis optica in Cuba . J Neurol 2009 ; 256 ( 1 ): 35 - 44 . doi: 10.1007/s00415-009-0009-0 https://dx.doi.org/10.1007/s00415-009-0009-0 . DOI: 10.1007/s00415-009-0009-0 http://doi.org/10.1007/s00415-009-0009-0
Asgari N , Lillevang ST , Skejoe HP , et al . A population-based study of neuromyelitis optica in Caucasians . Neurology 2011 ; 76 ( 18 ): 1589 - 95 . doi: 10.1212/ 10.1212/WNL.0b013e3182190f74 https://dx.doi.org/10.1212/WNL.0b013e3182190f74 . DOI: 10.1212/WNL.0b013e3182190f74 http://doi.org/10.1212/WNL.0b013e3182190f74
Flanagan EP , Cabre P , Weinshenker BG , et al . Epidemiology of aquaporin-4 autoimmunity and neuromyelitis optica spectrum . Ann Neurol 2016 ; 79 ( 5 ): 775 - 83 . doi: 10.1002/ana.24617 https://dx.doi.org/10.1002/ana.24617 . DOI: 10.1002/ana.24617 http://doi.org/10.1002/ana.24617
Bukhari W , Prain KM , Waters P , et al . Incidence and prevalence of NMOSD in Australia and New Zealand . J Neurol Neurosurg Psychiatry 2017 ; 88 ( 8 ): 632 . doi: 10.1136/jnnp-2016-314839 https://dx.doi.org/10.1136/jnnp-2016-314839 . DOI: 10.1136/jnnp-2016-314839 http://doi.org/10.1136/jnnp-2016-314839
Lennon VA , Wingerchuk DM , Kryzer TJ , et al . A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis . Lancet 2004 ; 364 ( 9451 ): 2106 - 12 . doi: 10.1016/S0140-6736(04)17551-X https://dx.doi.org/10.1016/S0140-6736(04)17551-X . DOI: 10.1016/S0140-6736(04)17551-X http://doi.org/10.1016/S0140-6736(04)17551-X
Jarius S1 , Wildemann B . Aquaporin-4 antibodies (NMO-IgG) as a serological marker of neuromyelitis optica: a critical review of the literature . Brain Pathol 2013 ; 23 ( 6 ): 661 - 83 . doi: 10.1111/bpa.12084 https://dx.doi.org/10.1111/bpa.12084 . DOI: 10.1111/bpa.12084 http://doi.org/10.1111/bpa.12084 http://doi.wiley.com/10.1111/bpa.2013.23.issue-6 http://doi.wiley.com/10.1111/bpa.2013.23.issue-6
Bennett JL , Lam C , Kalluri SR , et al . Intrathecal pathogenic anti-aquaporin-4 antibodies in early neuromyelitis optica . Ann Neurol 2009 ; 66 ( 5 ): 617 - 29 . doi: 10.1002/ana.21802 https://dx.doi.org/10.1002/ana.21802 . DOI: 10.1002/ana.21802 http://doi.org/10.1002/ana.21802 http://doi.wiley.com/10.1002/ana.v66%3A5 http://doi.wiley.com/10.1002/ana.v66%3A5
Bradl M , Misu T , Takahashi T , et al . Neuromyelitis optica: pathogenicity of patient immunoglobulin in vivo . Ann Neurol 2009 ; 66 ( 5 ): 630 - 43 . doi: 10.1002/ana.21837 https://dx.doi.org/10.1002/ana.21837 . DOI: 10.1002/ana.21837 http://doi.org/10.1002/ana.21837 http://doi.wiley.com/10.1002/ana.v66%3A5 http://doi.wiley.com/10.1002/ana.v66%3A5
Huang W , Zhang Bao J , Chang X , et al . Neuromyelitis optica spectrum disorder in China: quality of life and medical care experience . Mult Scler Relat Disord 2020 ; 46 : 102542 . doi: 10.1016/j.msard.2020.102542 https://dx.doi.org/10.1016/j.msard.2020.102542 . DOI: 10.1016/j.msard.2020.102542 http://doi.org/10.1016/j.msard.2020.102542 https://linkinghub.elsevier.com/retrieve/pii/S2211034820306167 https://linkinghub.elsevier.com/retrieve/pii/S2211034820306167
Pellkofer HL , Havla J , Hauer D , et al . The major brain endocannabinoid 2-AG controls neuropathic pain and mechanical hyperalgesia in patients with neuromyelitis optica . PLoS One 2013 ; 8 ( 8 ): e71500 . doi: 10.1371/journal.pone.0071500 https://dx.doi.org/10.1371/journal.pone.0071500 . DOI: 10.1371/journal.pone.0071500 http://doi.org/10.1371/journal.pone.0071500 https://dx.plos.org/10.1371/journal.pone.0071500 https://dx.plos.org/10.1371/journal.pone.0071500
Asseyer S , Schmidt F , Chien C , et al . Pain in AQP4-IgG-positive and MOG-IgG-positive neuromyelitis optica spectrum disorders . Mult Scler J Exp Transl Clin 2018 ; 4 ( 3 ): 2055217318796684 . doi: 10.1177/2055217318796684 https://dx.doi.org/10.1177/2055217318796684 . DOI: 10.1177/2055217318796684 http://doi.org/10.1177/2055217318796684
Zhao S , Mutch K , Elsone L , et al . Neuropathic pain in neuromyelitis optica affects activities of daily living and quality of life . Mult Scler 2014 ; 20 ( 12 ): 1658 - 61 . doi: 10.1177/1352458514522103 https://dx.doi.org/10.1177/1352458514522103 . DOI: 10.1177/1352458514522103 http://doi.org/10.1177/1352458514522103 http://journals.sagepub.com/doi/10.1177/1352458514522103 http://journals.sagepub.com/doi/10.1177/1352458514522103
Kong Y , Okoruwa H , Revis J , et al . Pain in patients with transverse myelitis and its relationship to aquaporin 4 antibody status . J Neurol Sci 2016 ; 368 : 84 - 8 . doi: 10.1016/j.jns.2016.06.041 https://dx.doi.org/10.1016/j.jns.2016.06.041 . DOI: 10.1016/j.jns.2016.06.041 http://doi.org/10.1016/j.jns.2016.06.041 https://linkinghub.elsevier.com/retrieve/pii/S0022510X16303720 https://linkinghub.elsevier.com/retrieve/pii/S0022510X16303720
Chavarro VS , Mealy MA , Simpson A , et al . Insufficient treatment of severe depression in neuromyelitis optica spectrum disorder . Neurol Neuroimmunol Neuroinflamm 2016 ; 3 ( 6 ): e286 . doi: 10.1212/NXI.0000000000000286 https://dx.doi.org/10.1212/NXI.0000000000000286 . DOI: 10.1212/NXI.0000000000000286 http://doi.org/10.1212/NXI.0000000000000286 http://nn.neurology.org/lookup/doi/10.1212/NXI.0000000000000286 http://nn.neurology.org/lookup/doi/10.1212/NXI.0000000000000286
Brody J , Hellmann MA , Marignier R , et al . Neuromyelitis optica spectrum disorder: disease course and long-term visual outcome . J Neuroophthalmol 2016 ; 36 ( 4 ): 356 - 62 . doi: 10.1097/WNO.0000000000000403 https://dx.doi.org/10.1097/WNO.0000000000000403 . DOI: 10.1097/WNO.0000000000000403 http://doi.org/10.1097/WNO.0000000000000403 https://journals.lww.com/00041327-201612000-00002 https://journals.lww.com/00041327-201612000-00002
Jarius S , Ruprecht K , Kleiter I , et al . MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome . J Neuroinflammation 2016 ; 13 ( 1 ): 280 . doi: 10.1186/s12974-016-0718-0 https://dx.doi.org/10.1186/s12974-016-0718-0 . DOI: 10.1186/s12974-016-0718-0 http://doi.org/10.1186/s12974-016-0718-0 http://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0718-0 http://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0718-0
Masuda H , Mori M , Uzawa A , et al . Validation of the Modified Fatigue Impact Scale and the relationships among fatigue, pain and serum interleukin-6 levels in patients with neuromyelitis optica spectrum disorder . J Neurol Sci 2018 ; 385 : 64 - 8 . doi: 10.1016/j.jns.2017.11.041 https://dx.doi.org/10.1016/j.jns.2017.11.041 . DOI: 10.1016/j.jns.2017.11.041 http://doi.org/10.1016/j.jns.2017.11.041 https://linkinghub.elsevier.com/retrieve/pii/S0022510X17344817 https://linkinghub.elsevier.com/retrieve/pii/S0022510X17344817
Mealy MA , Boscoe A , Caro J , et al . Assessment of patients with neuromyelitis optica spectrum disorder using the EQ-5D . Int J MS Care 2019 ; 21 ( 3 ): 129 - 34 . doi: 10.7224/1537-2073.2017-076 https://dx.doi.org/10.7224/1537-2073.2017-076 . DOI: 10.7224/1537-2073.2017-076 http://doi.org/10.7224/1537-2073.2017-076 https://meridian.allenpress.com/ijmsc/article/21/3/129/12039/Assessment-of-Patients-with-Neuromyelitis-Optica https://meridian.allenpress.com/ijmsc/article/21/3/129/12039/Assessment-of-Patients-with-Neuromyelitis-Optica
Chanson JB , Zéphir H , Collongues N , et al . Evaluation of health-related quality of life, fatigue and depression in neuromyelitis optica . Eur J Neurol 2011 ; 18 ( 6 ): 836 - 41 . doi: 10.1111/j.1468-1331.2010.03252.x https://dx.doi.org/10.1111/j.1468-1331.2010.03252.x . DOI: 10.1111/j.1468-1331.2010.03252.x http://doi.org/10.1111/j.1468-1331.2010.03252.x
Seok JM , Choi M , Cho EB , et al . Fatigue in patients with neuromyelitis optica spectrum disorder and its impact on quality of life . PLoS One 2017 ; 12 ( 5 ): e0177230 . doi: 10.1371/journal.pone.0177230 https://dx.doi.org/10.1371/journal.pone.0177230 . DOI: 10.1371/journal.pone.0177230 http://doi.org/10.1371/journal.pone.0177230 https://dx.plos.org/10.1371/journal.pone.0177230 https://dx.plos.org/10.1371/journal.pone.0177230
Qian P , Lancia S , Alvarez E , et al . Association of neuromyelitis optica with severe and intractable pain . Arch Neurol 2012 ; 69 ( 11 ): 1482 - 7 . doi: 10.1001/ archneurol.2012.768 https://dx.doi.org/10.1001/ archneurol.2012.768 . DOI: 10.1001/ archneurol.2012.768 http://doi.org/10.1001/ archneurol.2012.768 http://archneur.jamanetwork.com/article.aspx?doi=10.1001/archneurol.2012.768 http://archneur.jamanetwork.com/article.aspx?doi=10.1001/archneurol.2012.768
Kanamori Y , Nakashima I , Takai Y , et al . Pain in neuromyelitis optica and its effect on quality of life: a cross-sectional study . Neurology 2011 ; 77 ( 7 ): 652 - 8 . DOI: 10.1212/WNL.0b013e318229e694 http://doi.org/10.1212/WNL.0b013e318229e694
Eaneff S , Wang V , Hanger M , et al . Patient perspectives on neuromyelitis optica spectrum disorders: data from the PatientsLikeMe online community . Mult Scler Relat Disord 2017 ; 17 : 116 - 22 . doi: 10.1212/WNL.0b013e318229e694 https://dx.doi.org/10.1212/WNL.0b013e318229e694 . DOI: 10.1212/WNL.0b013e318229e694 http://doi.org/10.1212/WNL.0b013e318229e694 https://linkinghub.elsevier.com/retrieve/pii/S2211034817301645 https://linkinghub.elsevier.com/retrieve/pii/S2211034817301645
Kim SM , Go MJ , Sung JJ , et al . Painful tonic spasm in neuromyelitis optica: incidence, diagnostic utility, and clinical characteristics . Arch Neurol 2012 ; 69 ( 8 ): 1026 - 31 . doi: 10.1001/archneurol.2012.112 https://dx.doi.org/10.1001/archneurol.2012.112 . DOI: 10.1001/archneurol.2012.112 http://doi.org/10.1001/archneurol.2012.112
Bradl M , Kanamori Y , Nakashima I , et al . Pain in neuromyelitis optica-prevalence, pathogenesis and therapy . Nat Rev Neurol 2014 ; 10 ( 9 ): 529 - 36 . doi: 10.1038/nrneurol.2014.129 https://dx.doi.org/10.1038/nrneurol.2014.129 . DOI: 10.1038/nrneurol.2014.129 http://doi.org/10.1038/nrneurol.2014.129 https://doi.org/10.1038/nrneurol.2014.129 https://doi.org/10.1038/nrneurol.2014.129
Mealy MA , Kozachik SL , Levy M . Review of treatment for central spinal neuropathic pain and its effect on quality of life: implications for neuromyelitis optica spectrum disorder . Pain Manag Nurs 2019 ; 20 ( 6 ): 580 - 91 . doi: 10.1016/j.pmn.2019.03.003 https://dx.doi.org/10.1016/j.pmn.2019.03.003 . DOI: 10.1016/j.pmn.2019.03.003 http://doi.org/10.1016/j.pmn.2019.03.003 https://linkinghub.elsevier.com/retrieve/pii/S1524904218304077 https://linkinghub.elsevier.com/retrieve/pii/S1524904218304077
Beekman J , Keisler A , Pedraza O , et al . Neuromyelitis optica spectrum disorder: patient experience and quality of life . Neurol Neuroinflamm 2019 ; 6 ( 4 ): e580 . doi: 10.1212/NXI.0000000000000580 https://dx.doi.org/10.1212/NXI.0000000000000580 . DOI: 10.1212/NXI.0000000000000580 http://doi.org/10.1212/NXI.0000000000000580
Misu T , Höftberger R , Fujihara K , et al . Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica . Acta Neuropathol 2013 ; 125 ( 6 ): 815 - 27 . doi: 10.1007/ s00401-013-111 https://dx.doi.org/s00401-013-111 ٦-7. DOI: s00401-013-111 http://doi.org/s00401-013-111 http://link.springer.com/10.1007/s00401-013-1116-7 http://link.springer.com/10.1007/s00401-013-1116-7
Lucchinetti CF , Mandler RN , McGavern D , et al . A role for humoral mechanisms in the pathogenesis of Devic’s neuromyelitis optica . Brain 2002 ; 125 ( Pt 7 ): 1450 - 61 . doi: 10.1093/brain/awf151 https://dx.doi.org/10.1093/brain/awf151 . DOI: 10.1093/brain/awf151 http://doi.org/10.1093/brain/awf151
Ikeda H , Stark J , Fischer H , et al . Synaptic amplifier of inflammatory pain in the spinal dorsal horn . Science 2006 ; 312 ( 5780 ): 1659 - 62 . doi: 10.1126/science. 1127233 https://dx.doi.org/10.1126/science. 1127233 . DOI: 10.1126/science. 1127233 http://doi.org/10.1126/science. 1127233 https://www.science.org/doi/10.1126/science.1127233 https://www.science.org/doi/10.1126/science.1127233
Drdla R , Gassner M , Gingl E , et al . Induction of synaptic long-term potentiation after opioid withdrawal . Science 2009 ; 325 ( 5937 ): 207 - 10 . DOI: 10.1126/science.1171759 http://doi.org/10.1126/science.1171759
Hinson SR , Roemer SF , Lucchinetti CF , et al . Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2 . J Exp Med 2008 ; 205 ( 11 ): 2473 - 81 . doi: 10.1126/science.1171759 https://dx.doi.org/10.1126/science.1171759 . DOI: 10.1126/science.1171759 http://doi.org/10.1126/science.1171759 https://rupress.org/jem/article/205/11/2473/40245/Aquaporin4binding-autoantibodies-in-patients-with https://rupress.org/jem/article/205/11/2473/40245/Aquaporin4binding-autoantibodies-in-patients-with
Marignier R , Nicolle A , Watrin C , et al . Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury . Brain 2010 ; 133 ( 9 ): 2578 - 91 . doi: 10.1093/brain/awq177 https://dx.doi.org/10.1093/brain/awq177 . DOI: 10.1093/brain/awq177 http://doi.org/10.1093/brain/awq177
Moga D , Hof PR , Vissavajjhala P , et al . Parvalbumin-containing interneurons in rat hippocampus have an AMPA receptor profile suggestive of vulnerablility to excitotoxicity . J Chem Neuroanat 2002 ; 23 ( 4 ): 249 - 53 . doi: 10.1016/s0891-0618(02)00012-1 https://dx.doi.org/10.1016/s0891-0618(02)00012-1 . DOI: 10.1016/s0891-0618(02)00012-1 http://doi.org/10.1016/s0891-0618(02)00012-1 https://linkinghub.elsevier.com/retrieve/pii/S0891061802000121 https://linkinghub.elsevier.com/retrieve/pii/S0891061802000121
Zeilhofer HU , Wildner H , Yévenes GE . Fast synaptic inhibition in spinal sensory processing and pain control . Physiol Rev 2012 ; 92 ( 1 ): 193 - 235 . doi: 10.1152/physrev.00043.2010 https://dx.doi.org/10.1152/physrev.00043.2010 . DOI: 10.1152/physrev.00043.2010 http://doi.org/10.1152/physrev.00043.2010
Janssen SP , Truin M , Van Kleef M , et al . Differential GABAergic disinhibition during the development of painful peripheral neuropathy . Neuroscience 2011 ; 184 : 183 - 94 . doi: 10.1016/j.neuroscience. 2011.03.060 https://dx.doi.org/10.1016/j.neuroscience. 2011.03.060 . DOI: 10.1016/j.neuroscience.2011.03.060 http://doi.org/10.1016/j.neuroscience.2011.03.060
Moore KA , Kohno T , Karchewski LA , et al . Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord . J Neurosci 2002 ; 22 ( 15 ): 6724 - 31 . doi: 10.1523/JNEUROSCI.22-15-06724.2002 https://dx.doi.org/10.1523/JNEUROSCI.22-15-06724.2002 . DOI: 10.1523/JNEUROSCI.22-15-06724.2002 http://doi.org/10.1523/JNEUROSCI.22-15-06724.2002 https://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.22-15-06724.2002 https://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.22-15-06724.2002
Albrecht J , Sidoryk-Węgrzynowicz M , Zielińska M , et al . Roles of glutamine in neurotransmission . Neuron Glia Biol 2010 ; 6 ( 4 ): 263 - 76 . doi: 10.1017/S1740925X11000093 https://dx.doi.org/10.1017/S1740925X11000093 . DOI: 10.1017/S1740925X11000093 http://doi.org/10.1017/S1740925X11000093
Basbaum AI , Bautista DM , Scherrer G , et al . Cellular and molecular mechanisms of pain . Cell 2009 ; 139 ( 2 ): 267 - 84 . doi: 10.1016/j.cell.2009.09.028 https://dx.doi.org/10.1016/j.cell.2009.09.028 . DOI: 10.1016/j.cell.2009.09.028 http://doi.org/10.1016/j.cell.2009.09.028
Rayner L , Hotopf M , Petkova H , et al . Depression in patients with chronic pain attending a specialised pain treatment centre: prevalence and impact on health care costs . Pain 2016 ; 157 ( 7 ): 1472 - 9 . doi: 10.1097/j.pain.0000000000000542 https://dx.doi.org/10.1097/j.pain.0000000000000542 . DOI: 10.1097/j.pain.0000000000000542 http://doi.org/10.1097/j.pain.0000000000000542 https://journals.lww.com/00006396-201607000-00013 https://journals.lww.com/00006396-201607000-00013
Mitchell ND , Baker GB . An update on the role of glutamate in the pathophysiology of depression . Acta Psychiatr Scand 2010 ; 122 ( 3 ): 192 - 210 . doi: 10.1111/j.1600-0447.2009.01529.x https://dx.doi.org/10.1111/j.1600-0447.2009.01529.x . DOI: 10.1111/j.1600-0447.2009.01529.x http://doi.org/10.1111/j.1600-0447.2009.01529.x http://doi.wiley.com/10.1111/acp.2010.122.issue-3 http://doi.wiley.com/10.1111/acp.2010.122.issue-3
Hashimoto K . The role of glutamate on the action of antidepressants . Prog Neuropsychopharmacol Biol Psychiatry 2011 ; 35 ( 7 ): 1558 - 68 . doi: 10.1016/j.pnpbp.2010.06.013 https://dx.doi.org/10.1016/j.pnpbp.2010.06.013 . DOI: 10.1016/j.pnpbp.2010.06.013 http://doi.org/10.1016/j.pnpbp.2010.06.013 https://linkinghub.elsevier.com/retrieve/pii/S0278584610002307 https://linkinghub.elsevier.com/retrieve/pii/S0278584610002307
Pehrson AL , Sanchez C . Altered γ-aminobutyric acid neurotransmission in major depressive disorder: a critical review of the supporting evidence and the influence of serotonergic antidepressants . Drug Des Devel Ther 2015 ; 9 : 603 - 24 . doi: 10.2147/DDDT.S62912 https://dx.doi.org/10.2147/DDDT.S62912 . DOI: 10.2147/DDDT.S62912 http://doi.org/10.2147/DDDT.S62912
Kanes S , Colquhoun H , Gunduz-Bruce H , et al . Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial . Lancet 2017 ; 390 ( 10093 ): 480 - 9 . doi: 10.1016/S0140-6736(17)31264-3 https://dx.doi.org/10.1016/S0140-6736(17)31264-3 . DOI: 10.1016/S0140-6736(17)31264-3 http://doi.org/10.1016/S0140-6736(17)31264-3 https://linkinghub.elsevier.com/retrieve/pii/S0140673617312643 https://linkinghub.elsevier.com/retrieve/pii/S0140673617312643
Benson C , Mifflin K , Kerr B , et al . Biogenic amines and the amino acids GABA and glutamate: relationships with pain and depression . Mod Trends Pharmacopsychiatry 2015 ; 30 : 67 - 79 . doi: 10.1159/000435933 https://dx.doi.org/10.1159/000435933 . DOI: 10.1159/000435933 http://doi.org/10.1159/000435933
Goffer Y , Xu D , Eberle SE , et al . Calcium-permeable AMPA receptors in the nucleus accumbens regulate depression-like behaviors in the chronic neuropathic pain state . J Neurosci 2013 ; 33 ( 48 ): 19034 - 44 . doi: 10.1523/JNEUROSCI.2454-13.2013 https://dx.doi.org/10.1523/JNEUROSCI.2454-13.2013 . DOI: 10.1523/JNEUROSCI.2454-13.2013 http://doi.org/10.1523/JNEUROSCI.2454-13.2013 https://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.2454-13.2013 https://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.2454-13.2013
Sałat K , Podkowa A , Malikowska N , et al . Novel, highly potent and in vivo active inhibitor of GABA transporter subtype 1 with anticonvulsant, anxiolytic, antidepressant and antinociceptive properties . Neuropharmacology 2017 ; 113 ( Pt A ): 331 - 42 . doi: 10.1016/j. neuropharm.2016.10.019 https://dx.doi.org/10.1016/j. neuropharm.2016.10.019 . DOI: 10.1016/j. neuropharm.2016.10.019 http://doi.org/10.1016/j. neuropharm.2016.10.019 https://linkinghub.elsevier.com/retrieve/pii/S0028390816304737 https://linkinghub.elsevier.com/retrieve/pii/S0028390816304737
Wingerchuk DM , Banwell B , Bennett JL , et al . International consensus diagnostic criteria for neuromye- litis optica spectrum disorders . Neurology 2015 ; 85 ( 2 ): 177 - 89 . doi: 10.1212/WNL.0000000000001729 https://dx.doi.org/10.1212/WNL.0000000000001729 . DOI: 10.1212/WNL.0000000000001729 http://doi.org/10.1212/WNL.0000000000001729
Abboud H , Petrak A , Mealy M , et al . Treatment of acute relapses in neuromyelitis optica: steroids alone versus steroids plus plasma exchange . Mult Scler 2016 ; 22 ( 2 ): 185 - 92 . doi: 10.1177/1352458515581438 https://dx.doi.org/10.1177/1352458515581438 . DOI: 10.1177/1352458515581438 http://doi.org/10.1177/1352458515581438 http://journals.sagepub.com/doi/10.1177/1352458515581438 http://journals.sagepub.com/doi/10.1177/1352458515581438
Watanabe S , Nakashima I , Misu T , et al . Therapeutic efficacy of plasma exchange in NMO-IgG-positive patients with neuromyelitis optica . Mult Scler 2007 ; 13 ( 1 ): 128 - 32 . doi: 10.1177/1352458506071174 https://dx.doi.org/10.1177/1352458506071174 . DOI: 10.1177/1352458506071174 http://doi.org/10.1177/1352458506071174 http://journals.sagepub.com/doi/10.1177/1352458506071174 http://journals.sagepub.com/doi/10.1177/1352458506071174
Elsone L , Panicker J , Mutch K , et al . Role of intravenous immunoglobin in the treatment of acute relapses of neuromyelitis optica: experience in 10 patients . Mult Scler 2014 ; 20 ( 4 ): 501 - 4 . doi: 10.1177/1352458513495938 https://dx.doi.org/10.1177/1352458513495938 . DOI: 10.1177/1352458513495938 http://doi.org/10.1177/1352458513495938
Selmaj K , Selmaj I . Novel emerging treatments for NMOSD . Neurol Neurochir Pol 2019 ; 53 ( 3 ): 317 - 26 . doi: 10.5603/PJNNS.a2019.0049 https://dx.doi.org/10.5603/PJNNS.a2019.0049 . DOI: 10.5603/PJNNS.a2019.0049 http://doi.org/10.5603/PJNNS.a2019.0049 https://journals.viamedica.pl/neurologia_neurochirurgia_polska/article/view/66106 https://journals.viamedica.pl/neurologia_neurochirurgia_polska/article/view/66106
Butler S . The triumvirate of co-morbid chronic pain, depression, and cognitive impairment: attacking this “chicken-and-egg” in novel ways . Scand J Pain 2017 ; 15 : 148 - 9 . doi: 10.1016/j.sjpain.2017.03.004 https://dx.doi.org/10.1016/j.sjpain.2017.03.004 . DOI: 10.1016/j.sjpain.2017.03.004 http://doi.org/10.1016/j.sjpain.2017.03.004 https://www.degruyter.com/document/doi/10.1016/j.sjpain.2017.03.004/html https://www.degruyter.com/document/doi/10.1016/j.sjpain.2017.03.004/html
Mealy MA , Kozachik SL , Cook LJ , et al . Scrambler therapy improves pain in neuromyelitis optica: a randomized controlled trial . Neurology 2020 ; 94 ( 18 ): e1900 - 7 . doi: 10.1212/WNL.0000000000009370 https://dx.doi.org/10.1212/WNL.0000000000009370 . DOI: 10.1212/WNL.0000000000009370 http://doi.org/10.1212/WNL.0000000000009370 http://www.neurology.org/lookup/doi/10.1212/WNL.0000000000009370 http://www.neurology.org/lookup/doi/10.1212/WNL.0000000000009370
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