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角蛋白在胃肠道肿瘤中的作用和研究进展
- Affiliations：
1. 1Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
2. 2Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100010, China
- Author bio：
*E-mail: pumchkangweiming@126.com.
- Funds：吴阶平医学基金会(320.6750.19020)
DOI：10.24920/003990
中图分类号：收稿日期：2021-08-30，
录用日期：2021-12-23，
网络出版日期：2022-03-09，
纸质出版日期：2022-03-31
- Accepted：
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欧阳思文, 康维明. 角蛋白在胃肠道肿瘤中的作用和研究进展[J]. 中国医学科学杂志（英文版）, 2022,37(1):73-78.
Ouyang Siwen, Kang Weiming. Research Advances in the Role of Keratins in Gastrointestinal Cancer[J]. Chinese medical sciences journal, 2022, 37(1): 73-78.
欧阳思文, 康维明. 角蛋白在胃肠道肿瘤中的作用和研究进展[J]. 中国医学科学杂志（英文版）, 2022,37(1):73-78. DOI： 10.24920/003990.
Ouyang Siwen, Kang Weiming. Research Advances in the Role of Keratins in Gastrointestinal Cancer[J]. Chinese medical sciences journal, 2022, 37(1): 73-78. DOI： 10.24920/003990.
摘要
胃肠道肿瘤的发病率和死亡率居高不下。尽管诊断和治疗技术在不断改进
胃肠道肿瘤的早期诊断、中期和晚期治疗、药物耐受性以及癌症复发和转移等问题仍构成巨大挑战。在本篇综述中
我们总结了角蛋白在胃肠道肿瘤中的作用和研究进展
希望它们能成为预测、诊断或治疗胃肠道肿瘤的有效生物标志物。
Abstract
The incidence and mortality rates of gastrointestinal (GI) cancer remain high. Despite constant improvements in diagnostic and therapeutic techniques
the early diagnosis
mid- and late-stage treatment
drug tolerance
and cancer recurrence and metastasis in GI cancer remain challenging. In this review article we summarize the recent research advance in the roles of keratins in GI cancer
with the hope that they will become efficient biomarkers for the prediction
diagnosis
or treatment of these malignancies.
关键词
Keywords
references
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