双眼脉络膜阻塞继发于抗磷脂综合征合并系统性红斑狼疮

张扬; 张顺华; 卞爱玲; 陈有信

doi:10.24920/J1001-9294.2017.049

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双眼脉络膜阻塞继发于抗磷脂综合征合并系统性红斑狼疮

中国医学科学杂志(英文版) 2017年32卷第4期页码：269-273

CASE REPORT | Updated：2024-04-10

- 双眼脉络膜阻塞继发于抗磷脂综合征合并系统性红斑狼疮
- Affiliations：
  
  Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
- Author bio：
  
  *Corresponding author Tel: 86-10-69151660, E-mail: chenyouxinpumch@163.com
- Funds：
- DOI：10.24920/J1001-9294.2017.049
  中图分类号：
- 收稿日期：2016-11-18，
  
  网络出版日期：2017-12-30，
  
  纸质出版日期：2017-12
- Accepted：
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张扬, 张顺华, 卞爱玲, 等. 双眼脉络膜阻塞继发于抗磷脂综合征合并系统性红斑狼疮[J]. 中国医学科学杂志(英文版), 2017,32(4):269-273.

Zhang Yang, Zhang Shunhua, Bian Ailing, et al. Bilateral Choroidal Occlusion in Antiphospholipid Syndrome Associated with Systemic Lupus Erythematosus[J]. Chinese medical sciences journal, 2017, 32(4): 269-273.
张扬, 张顺华, 卞爱玲, 等. 双眼脉络膜阻塞继发于抗磷脂综合征合并系统性红斑狼疮[J]. 中国医学科学杂志(英文版), 2017,32(4):269-273. DOI： 10.24920/J1001-9294.2017.049.

Zhang Yang, Zhang Shunhua, Bian Ailing, et al. Bilateral Choroidal Occlusion in Antiphospholipid Syndrome Associated with Systemic Lupus Erythematosus[J]. Chinese medical sciences journal, 2017, 32(4): 269-273. DOI： 10.24920/J1001-9294.2017.049.

摘要

本文报告了1例合并系统性红斑狼疮（SLE）的抗磷脂综合征（APS）患者

并发双眼脉络膜阻塞的罕见病例。患者女性

24岁

双眼视力快速进行性下降

经眼科检查诊断为双眼脉络膜阻塞。影像检查发现腹主动脉血栓

双侧髂动脉阻塞。患者伴有多次流产病史。给予患者糖皮质激素、免疫抑制剂及抗凝联合治疗后

患者视功能有所改善。合并系统性红斑狼疮的抗磷脂综合征患者眼部有血栓形成的风险

可累及不同管径的眼部血管

包括视网膜动静脉。本病例提示眼科、风湿科医师

SLE相关的APS患者发生血管栓塞可以累及脉络膜

甚至双眼同时发病

导致视功能的损害

需早期积极的治疗。

Abstract

This article reports a rare case of bilateral choroidal occlusion that occurred in a 24-year-old woman with antiphospholipid syndrome (APS) associated with systemic lupus erythematosus (SLE). This young lady concurred with aorta ventralis thrombosis and bilateral iliac artery occlusion when presented

and experienced a rapid deterioration of vision. She also has a history of recurrent miscarriage. Corticosteroid

immunosuppression and anticoagulation therapy were administered. Patients with APS associated with SLE are at risk for thrombotic phenomena

which may affect the ocular vessels of all sizes

including choroidal vessel. Our case alerts ophthalmologists and rheumatologists that bilateral choroidal occlusion may indeed be developed in patients with APS associated with SLE

and is a potential cause of visual morbidity.

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references

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