Chinese Medical Sciences Journal ›› 2017, Vol. 32 ›› Issue (4): 269-273.doi: 10.24920/J1001-9294.2017.049

• CASE REPORT • Previous Articles     Next Articles

Bilateral Choroidal Occlusion in Antiphospholipid Syndrome Associated with Systemic Lupus Erythematosus

Zhang Yang, Zhang Shunhua, Bian Ailing, Chen Youxin*()   

  1. Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
  • Received:2016-11-18 Online:2017-12-30 Published:2017-12-30
  • Contact: Chen Youxin E-mail:chenyouxinpumch@163.com
This article reports a rare case of bilateral choroidal occlusion that occurred in a 24-year-old
woman with antiphospholipid syndrome (APS) associated with systemic lupus erythematosus (SLE), which alerts ophthalmologists and rheumatologists that bilateral choroidal occlusion may indeed occurred in this special condition and cause visual morbidity.

Abstract:

This article reports a rare case of bilateral choroidal occlusion that occurred in a 24-year-old woman with antiphospholipid syndrome (APS) associated with systemic lupus erythematosus (SLE). This young lady concurred with aorta ventralis thrombosis and bilateral iliac artery occlusion when presented, and experienced a rapid deterioration of vision. She also has a history of recurrent miscarriage. Corticosteroid, immunosuppression and anticoagulation therapy were administered. Patients with APS associated with SLE are at risk for thrombotic phenomena, which may affect the ocular vessels of all sizes, including choroidal vessel. Our case alerts ophthalmologists and rheumatologists that bilateral choroidal occlusion may indeed be developed in patients with APS associated with SLE, and is a potential cause of visual morbidity.

Key words: anticardiolipin antibodies, antiphospholipid antibodies, choroidal vessels, systemic lupus erythematosus

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