国际经验与中国道路：中国脊髓灰质炎活疫苗制造及检定规程制定的历史与启示

doi:10.24920/004284

摘要/Abstract

摘要：

脊髓灰质炎的消灭是公共卫生史上的一个创举，有力地护佑了儿童健康。中国本土脊髓灰质炎活疫苗制造及检定规程的出台是国产活疫苗大规模应用的前提和保障，是疫苗安全生产必不可少的环节。本文结合档案、书信、论文集、口述访谈等资料，考察中国脊髓灰质炎活疫苗制造及检定规程制定的历史过程与经验，认为在充分开展国际合作的同时注重本土化是中国脊髓灰质炎活疫苗制造及检定规程得以快速出台的关键因素。

关键词: 脊髓灰质炎活疫苗检定规程, 国际合作, 本土化, 顾方舟

Abstract:

The eradication of poliomyelitis is a landmark achievement in the history of public health, providing strong protection for children’s health. The introduction of the Chinese Regulations for the Manufacture and Control of Live Poliovirus Vaccine is a prerequisite and safeguard for the large-scale production and use of domestically produced live poliovirus vaccines, serving as an indispensable component of vaccine safety. This article, based on archival documents, letters, collections of essays, and oral interviews, examines the historical experience of the development of Chinese Regulations for the Manufacture and Control of Live Poliovirus Vaccine. It contends that the emphasis on localization and the active engagement in international cooperation are critical factors in the swift introduction of Chinese Regulations for the Manufacture and Control of Live Poliovirus Vaccine.

Key words: Chinese Regulations for the Manufacture and Control of Live Poliovirus Vaccine, international cooperation, localization, Gu Fang Zhou

Miao Wu. Regulations for the Manufacture and Control of Live Poliovirus Vaccine: International Experience and China’s Path[J].Chinese Medical Sciences Journal, 2023, 38(4): 315-320.

图/表 1

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