Chinese Medical Sciences Journal ›› 2010, Vol. 25 ›› Issue (3): 185-188.doi: 10.1016/S1001-9294(10)60046-6

• Original Article • Previous Articles     Next Articles

Non-Hodgkin’s Lymphoma Primarily Presenting with Fanconi Syndrome and Acute Kidney Injury

Wen-ling Ye1*, Bing Han2, Bing-yan Liu1, Chan Meng1, Wei Ye1, Yu-bing Wen1, Hang Li1, and Xue-mei Li1   

  1. 1Department of Medicine, 2Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
  • Received:2010-05-19 Online:2010-09-20 Published:2010-09-20
  • About author:Tel: 86-10-65295058

Abstract: KIDNEY involvement is common in non-Hodgkin's lymphoma (NHL) with incidence up to 30%-40% in autopsy studies.1 However, it us- ually occurs late in the course of the disease and is clinically silent. Clinically overt renal disease including acute kidney injury (AKI) as its primary manifestation is rarely reported, moreover, Fanconi syndrome (FS) is extremely rare as the main manifestation in NHL. In this report, we presented a case of NHL primarily presenting with FS and AKI due to diffuse interstitial infiltration of NHL cells and emphasized the important role of renal biopsy, especially renal immunohistochemical analysis in the diagnosis of renal diffuse lymphoma.

Key words: non-Hodgkin's lymphoma, Fanconi syndrome, acute kidney injury

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