1. |
Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics. Science 2002; 297(5580):353-6. doi: 10.1126/science.1072994.
doi: 10.1126/science.1072994
pmid: 12130773
|
2. |
Gouras GK, Tsai J, Naslund J, et al. Intraneuronal A-beta 42 accumulation in human brain. Am J Pathol 2000; 156(1):15-20. doi: 10.1016/s0002-9440(10)64700-1.
pmid: 10623648
|
3. |
Williamson J, Goldman J, Marder KS. Genetic aspects of Alzheimer disease. Neurologist 2016; 15(2):80. doi: 10.1097/NRL.0b013e318187e76b.
|
4. |
Langfelder P, Horvath S. WGCNA: an R package for weighted correlation network analysis. BMC bioinforma-tics 2008; 9(1):559. doi: 10.1186/1471-2105-9-559.
|
5. |
Ritchie ME, Phipson B, Wu D, et al. Limma powers differential expression analyses for RNA-sequen-cing and microarray studies. Nucleic Acids Res 2015; 43(7):e47. doi: 10.1093/nar/gkv007.
|
6. |
Zhang B, Horvath S. A general framework for weighted gene co-expression newtork analysis. Sta Appl Genet Mol Biol 2005; 4:Article 17. doi: 10.2202/1544-6115.1128.
|
7. |
Zheng CH, Yuan L, Sha W, et al. Gene differential coexpression analysis based on biweight correlation and maximum clique. BMC bioinformatics 2014; 15(Suppl 15):S3. doi: 10.1186/1471-2105-15-S15-S3.
|
8. |
Horvath S, Dong J, Miyano S. Geometric interpretation of gene coexpression network analysis. PLoS comput biol 2008; 4(8):e1000117. doi: 10.1371/journal.pcbi.1000117.
pmid: 18704157
|
9. |
Zhou Y, Zhou B, Pache L, et al. Metascape provides a biologist-oriented resource for the analysis of systems-level datasets. Nat Commun 2019; 10(1):1523. doi: 10.1038/s41467-019-09234-6.
|
10. |
Shannon P. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res 2003; 13(11):2498. doi: 10.1101/gr.1239303.
pmid: 14597658
|
11. |
Szklarczyk D, Franceschini A, Kuhn M, et al. The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored. Nucleic Acids Res 2011; 39(database issue):D561-8. doi: 10.1093/nar/gkq973.
|
12. |
Liu ZP, Wang Y, Zhang XS, et al. Network-based ana-lysis of complex diseases. IET Syst Biol 2012; 6(1):22-33. doi: 10.3390/ iet-syb.2010.0052.
pmid: 22360268
|
13. |
Liu ZP, Wang Y, Zhang XS, et al. Detecting and analyzing differentially activated pathways in brain regions of Alzheimer’s disease patients. Mol Bio Syst 2011; 7(5):1441-52. doi: 10.1039/c0mb00325e.
|
14. |
Liu ZP, Wang Y, Zhang XS, et al. Identifying dysfunctional crosstalk of pathways in various regions of Alzheimer’s disease brains. BMC Syst Biol 2010; 4(Suppl 2):S11. doi: 10.1186/1752-0509-4-S2-S11.
|
15. |
Ficz G. New insights into mechanisms that regulate DNA methylation patterning. J Exp Biol 2015; 218(Pt 1):14-20. doi: 10.1242/jeb.107961.
|
16. |
Yu NK, Beak SH, Kaang BK. DNA methylation-mediated control of learning and memory. Mol Brain 2011; 4:5. doi: 10.1186/1756-6606-4-5.
|
17. |
Lando M, Fjeldbo CS, Wilting SM, et al. Interplay between promoter methylation and chromosomal loss in gene silencing at 3p11-p14 in cervical cancer. Epigenetics 2015; 10(10):970-80. doi: 10.1080/15592294.2015.1085140.
doi: 10.1080/15592294.2015.1085140
pmid: 26291246
|
18. |
Van GM, Baranger K, Benech P, et al. Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer’s disease: Alleviation by pantethine. PloS One 2018; 12(4):e0175369. doi: 10.1371/journal.pone.0175369.
|
19. |
Akihiro Y, Takagi H, Kimata D, et al. Deficiency in protein L-iso-aspartyl methyltaransferase results in a fatal progressive epilepsy. J Neurosci 1998; 18(6):2063-74. doi: 10.1016/S0165-5728(97)00232-4.
pmid: 9482793
|
20. |
Shimizu T, Watanabe A, Ogawara M, et al. Isoaspartate formation and neurodegeneration in Alzheimer’s disease. Arch Biochem Biophys 2000; 381(2):225-34. doi: 10.1006/abbi.2000.1955.
pmid: 11032409
|
21. |
Pawlosky RJ, Kemper MF, Kashiwaya Y, et al. Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer’s disease. J Neurochem 2017; 141(2):195-207. doi: 10.1111/jnc.13958.
doi: 10.1111/jnc.2017.141.issue-2
pmid: 28099989
|
22. |
Russell H. Swerdlow. Mitochondria and mitochondrial cascades in Alzheimer’s disease. J Alzheimers Dis 2017; 62(3):1403-16. doi: 10.3233/JAD-170585.
|
23. |
Han Y, Chu X, Cui L, et al. Neuronal mitochondria-targeted therapy for Alzheimer’s disease by systemic delivery of resveratrol using dual-modified novel biomimetic nanosystems. Drug Deliv 2020; 27(1):502-18. doi: 10.1080/10717544.2020.1745328.
doi: 10.1080/10717544.2020.1745328
pmid: 32228100
|
24. |
Gao C, Wang Y, Sun J, et al. Neuronal mitochondria-targeted delivery of curcumin by biomimetic engineered nanosystems in Alzheimer’s disease mice. Acta Biomater 2020; 108:285-99. doi: 10.1016/j.actbio.2020.03.029.
|
25. |
Khosravi S, Harner ME. The MICOS complex, a structural element of mitochondria with versatile functions. Biol Chem 2020; 401(6-7):765-78. doi: 10.1515/hsz-2020-0103.
doi: 10.1515/hsz-2020-0103
pmid: 32229686
|
26. |
van Gijsel-Bonnello M, Baranger K, Benech P, et al. Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer’s disease: Alleviation by pantethine. PLoS One 2017; 12(4):e0175369. doi: 10.1371/journal.pone.0175369. Erratum in PLoS One 2018; 13(3):e0194586.
doi: 10.1371/journal.pone.0175369
pmid: 28410378
|
27. |
Dong Y, Brewer GJ. Global metabolic shifts in age and Alzheimer’s disease mouse brains pivot at NAD+/NADH redox sites. J Alzheimers Dis 2019; 71(1):119-40. doi: 10.3233/JAD-190408.
doi: 10.3233/JAD-190408
pmid: 31356210
|
28. |
Fassio A, Esposito A, Kato M, et al. De novo mutations of the ATP6V1A gene cause developmental encephalopathy with epilepsy. Brain 2018; 141(6):1703-18. doi: 10.1093/brain/awy092.
doi: 10.1093/brain/awy092
pmid: 29668857
|
29. |
Palmieri F. The mitochondrial transporter family SLC25: identification, properties and physiopathology. Mol Aspects Med 2013; 34(2-3):465-84. doi: 10.1016/j.mam.2012.05.005.
doi: 10.1016/j.mam.2012.05.005
pmid: 23266187
|
30. |
Anitha A, Nakamura K, Thanseem I, et al. Brain region-specific altered expression and association of mitochondria-related genes in autism. Mol Autism 2012; 3(1):12. doi: 10.1186/2040-2392-3-12.
doi: 10.1186/2040-2392-3-12
pmid: 23116158
|
31. |
Shafqat N, Kavanagh KL, Sass JO, et al. A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency. J Inherit Metab Dis 2013; 36(6):983-7. doi: 10.1007/s10545-013-9589-z.
doi: 10.1007/s10545-013-9589-z
pmid: 23420214
|