玻璃体腔内注射抗血管内皮生长因子治疗非典型类癌的虹膜睫状体转移瘤

doi:10.24920/004268

Chinese Medical Sciences Journal ›› 2023, Vol. 38 ›› Issue (4): 305-308.doi: 10.24920/004268

玻璃体腔内注射抗血管内皮生长因子治疗非典型类癌的虹膜睫状体转移瘤

张扬,卞爱玲,戴荣平()

中国医学科学院北京协和医学院北京协和医院眼科，北京 100730

收稿日期:2023-06-05 接受日期:2023-10-08 出版日期:2023-12-30 发布日期:2023-11-02
通讯作者: 戴荣平 E-mail:derricka@sina.com

Iridociliary Body Metastasis of Atypical Carcinoid: Case Management with Intravitreal Anti-Vascular Endothelial Growth Factor Injections

Yang Zhang,Ai-Ling Bian,Rong-Ping Dai()

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Received:2023-06-05 Accepted:2023-10-08 Published:2023-12-30 Online:2023-11-02
Contact: Rong-Ping Dai E-mail:derricka@sina.com

摘要/Abstract

摘要：

52岁女性被诊断为非典型支气管类癌，伴纵隔、纵隔淋巴结、乳腺和胰腺转移。虹膜和睫状体的转移瘤导致患者左眼视力逐渐下降。经玻璃体腔内注射抗血管内皮生长因子治疗，取得了理想的治疗效果。

关键词: 非典型类癌肿瘤, 神经内分泌肿瘤, 虹膜转移, 玻璃体腔注射

Abstract:

We report a rare case involving a 52-year-old female diagnosed with an atypical bronchial carcinoid tumor with metastases to the mediastinum, hilar lymph nodes, breast, and pancreas. In additional, the patient had metastases to the iris and ciliary body, resulting in progressive vision loss in her left eye. Treatment was successful by intravitreal injections of anti-vascular endothelial growth factor.

Key words: atypical bronchial carcinoid tumor, neuroendocrine tumor, iris metastasis, intravitreal injection

Yang Zhang,Ai-Ling Bian,Rong-Ping Dai. Iridociliary Body Metastasis of Atypical Carcinoid: Case Management with Intravitreal Anti-Vascular Endothelial Growth Factor Injections[J].Chinese Medical Sciences Journal, 2023, 38(4): 305-308.

图/表 4

参考文献 9.

1.	Pelosi G, Sonzogni A, Harari S, et al. Classification of pulmonary neuroendocrine tumors: new insights. Transl Lung Cancer Res 2017; 6(5):513-29. doi: 10.21037/tlcr.2017.09.04.
2.	Shah SU, Mashayekhi A, Shields CL, et al. Uveal metastasis from lung cancer: clinical features, treatment, and outcome in 194 patients. Ophthalmology 2014; 121(1):352-7. doi: 10.1016/j.ophtha.2013.07.014. pmid: 23988200
3.	Shields CL, Kaliki S, Crabtree GS, et al. Iris metastasis from systemic cancer in 104 patients: the 2014 Jerry A. Cornea 2015; 34(1):42-8. doi: 10.1097/ICO.0000000000000285. pmid: 25343701
4.	Nagendran ST, Finger PT. Anti-VEGF intravitreal bevacizumab for radiation-associated neovascular glaucoma. Ophthalmic Surg Lasers Imaging Retina 2015; 46(2):201-7. doi: 10.3928/23258160-20150213-08.
5.	Raval V, Saldanha M, Mittal R, et al. Intravitreal bevacizumab in treatment of iris metastasis from primary lung carcinoma. BMJ Case Rep 2019; 12(9): e231097. doi: 10.1136/bcr-2019-231097.
6.	Hidaka T, Chuman H, Nao IN. A case report of intravitreal bevacizumab for iris metastasis of small cell lung carcinoma with neovascular glaucoma. Case Rep Ophthalmol 2018; 9(2):401-4. doi: 10.1159/000492713.
7.	Nakashima C, Keino H, Watanabe T, et al. Intravitreal bevacizumab for iris metastasis of small-cell lung carcinoma with neovascular glaucoma. Jpn J Ophthalmol 2011; 55(1):80-1. doi: 10.1007/s10384-010-0892-z. pmid: 21331703
8.	Wolf A, von Jagow B, Ulbig M, et al. Intracameral injection of bevacizumab for the treatment of neovascular glaucoma. Ophthalmologica 2011; 226(2):51-6. doi: 10.1159/000327364. pmid: 21546781
9.	Maudgil A, Sears KS, Rundle PA, et al. Failure of intravitreal bevacizumab in the treatment of choroidal metastasis. Eye (Lond) 2015; 29(5):707-11. doi: 10.1038/eye.2015.21.

[1]	李铁力, 丁海璇, 赵新兰, 罗娟, 陈凯, 唐卓, 黄凌云, 李浪波, 杨丽. MODY₃合并肠道神经内分泌肿瘤：1例病例报道[J]. Chinese Medical Sciences Journal, 2022, 37(2): 167-170.
[2]	王亮, 李刚, 邴运韬, 田茂霖, 王行雁, 原春辉, 修典荣. 既往癌症对局限性胰腺神经内分泌肿瘤患者的生存结果有影响吗?[J]. Chinese Medical Sciences Journal, 2021, 36(4): 284-294.
[3]	李刚, 邴运韬, 田茂霖, 原春辉, 修典荣. 使用列线图预测老年胰腺神经内分泌肿瘤患者手术前远处转移的风险[J]. Chinese Medical Sciences Journal, 2021, 36(3): 218-224.
[4]	王英伟, 张兴华, 王波涛, 王叶, 刘梦琦, 王海屹, 叶慧义. 体素内不相干运动成像参数的纹理分析在胰腺神经内分泌肿瘤和胰腺癌鉴别诊断中的价值[J]. Chinese Medical Sciences Journal, 2019, 34(1): 1-9.

优先出版

当期目次

过刊浏览

虚拟专题

作者中心

评阅者中心

玻璃体腔内注射抗血管内皮生长因子治疗非典型类癌的虹膜睫状体转移瘤

Iridociliary Body Metastasis of Atypical Carcinoid: Case Management with Intravitreal Anti-Vascular Endothelial Growth Factor Injections

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

图/表 4

参考文献 9.

相关文章 4

Metrics

推荐阅读 10