Chinese Medical Sciences Journal ›› 2020, Vol. 35 ›› Issue (2): 170-178.doi: 10.24920/003540
• Original Article • Previous Articles Next Articles
Xu Longming1, Dai Shuiping2, Zuo Yunxia1, *()
Received:
2019-07-08
Accepted:
2020-03-29
Published:
2020-06-30
Contact:
Zuo Yunxia
E-mail:zuoyxhxa@163.com
Xu Longming,Dai Shuiping,Zuo Yunxia. Impacts of Preoperative Smoking and Smoking Cessation Time on Preoperative Peripheral Blood Inflammatory Indexes and Postoperative Hospitalization Outcome in Male Patients with Lung Cancer and Surgery Treatment[J].Chinese Medical Sciences Journal, 2020, 35(2): 170-178.
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Table 1
Baseline characteristics of patients with lung cancer in different groups of smoking status and smoking cessation time"
Characteristics | Current smoker (n=177) | Ex-smoker (n=372) | Never- smoker (n=88) | F/X2 | P | ||||
---|---|---|---|---|---|---|---|---|---|
CeT≤6w (n=90) | 6w<CeT≤1y (n=107) | 1y<CeT≤5y (n=86) | 5y<CeT≤10y (n=34) | CeT>10y (n=55) | |||||
Age [years, mean(SD)] | 57.9 (8.0) | 59.9 (8.6) | 58.1 (8.5) | 60.7 (8.4) | 63.7 (7.2) | 64.8 (10.7) | 57.7 (13.3) | 4.525 | 0.000 |
BMI [kg/m2, mean (SD)] | 22.7 (3.3) | 22.9 (2.9) | 22.9 (2.9) | 23.1 (2.9) | 24.1 (2.3) | 23.2 (2.7) | 23.5 (2.6) | 1.049 | 0.537 |
8th edition IASLC Classification [n (%)] | 26.079 | 0.098 | |||||||
StageⅠ | 32 (18.1) | 18 (20.0) | 14 (13.1) | 18 (20.9) | 6 (17.6) | 6 (17.6) | 19 (21.6) | ||
Stage Ⅱ | 46 (26.0) | 32 (35.6) | 41 (38.3) | 31 (36) | 12 (35.3) | 9 (16.4) | 25 (28.4) | ||
Stage Ⅲ | 93 (52.5) | 36 (40.0) | 42 (39.3) | 33 (38.4) | 13 (38.2) | 32 (58.2) | 38 (43.2) | ||
Stage Ⅳ | 6 (3.4) | 4 (4.4) | 10 (9.3) | 4 (4.7) | 3 (8.8) | 1 (1.8) | 6 (6.8) | ||
Surgery procedures [n (%)] | 9.888 | 0.626 | |||||||
Lobectomy | 165 (93.2) | 85 (94.4) | 102 (95.3) | 79 (91.9) | 31 (91.2) | 47 (85.5) | 82 (93.2) | ||
Segmentec- tomy/wedge | 110 (5.6) | 4 (4.4) | 5 (4.7) | 7 (8.1) | 3 (8.8) | 7 (12.7) | 6 (6.8) | ||
Sleeve | 1 (1.1) | 1 (1.1) | 0 (0) | 0 (0) | 0 (0) | 1 (1.8) | 0 (0) |
Table 2
Comparisons of the inflammatory indexes and postoperative outcomes of lung cancer patients among groups of current smokers, ex-smokers and never smokers"
Variables | Never-smokers (n=88) | Ex-smokers (n=372) | Current smokers (n=177) | F/X2 | P |
---|---|---|---|---|---|
WBC [×109/L, mean (SD)] | 5.9 (1.4)**? | 7.0(2.6)* | 7.7(3.4) | 13.277 | 0.000 |
Albumin [g/L, mean (SD)] | 43.2 (3.5)**? | 42.1(4.3)* | 41.1(4.6) | 7.040 | 0.001 |
NLR [mean(SD)] | 2.8 (1.1)* | 3.1(1.9)* | 3.7(3.9) | 4.727 | 0.009 |
PLR [mean(SD)] | 132.6 (55.7) | 134.9(68.8) | 146.7(89.9) | 1.625 | 0.198 |
Blood loss [mL, mean(SD)] | 153.8 | 186.8 | 185.2 | 0.473 | 0.623 |
Placement time of closed thoracic drainage tube (days, median) | 4 | 4 | 6 | 1.450 | 0.235 |
ICU admission days (days, median) | 2 | 2 | 3 | 0.963 | 0.382 |
In-hospital days (days, median) | 9 | 10 | 11 | 0.308 | 0.735 |
Hospitalization costs [RMB Yuan, mean(SD)] | 60 546.8 (30 060.6) | 64 466.8 (33 187.1) | 71 072.9 (81 904.9) | 1.522 | 0.219 |
30-day mortality (%) # | 1.1 | 3.0 | 2.8 | 0.659 | 0.743 |
Table 3
Comparisons of the inflammatory indexes of lung cancer patients and postoperative outcomes of cancer patients among groups of different smoking status and smoking cessation time"
Variables | Current smokers (n=88) | Ex-smokers (n=372) | Never- smokers (n=177) | X2/F* | P* | X2/F? | P? | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
CeT≤6w (n=90) | 6w<CeT≤1y (n=107) | 1y<CeT≤5y (n=86) | 5y<CeT≤10y (n=34) | CeT>10y (n=55) | |||||||
WBC [×109/L, mean (SD)] | 7.7(3.4) | 7.5(2.5) | 7.1(3.1) | 6.6(2.0) | 6.8(2.8) | 6.8(2.6) | 5.9(1.4) | 5.275 | 0.000 | 1.362 | 0.247 |
Albumin [g/L, mean(SD)] | 41.7(4.4) | 41.4(3.9) | 41.7(5.4) | 41.6(4.1) | 43.9(3.1) | 42.2 (4.0) | 43.3 (3.3) | 2.470 | 0.023 | 2.072 | 0.084 |
PLR [mean(SD)] | 146.5 (89.9) | 117.4 (45.4) | 136.9 (75.2) | 138.8 (71.3) | 147.4 (78.6) | 144.7 (73.5) | 132.6 (55.7) | 1.709 | 0.116 | 2.008 | 0.093 |
NLR[mean(SD)] | 3.7(3.9) | 2.9(1.5) | 3.2(2.5) | 3.1(1.6) | 3.2(1.7) | 3.3(1.8) | 2.8(1.1) | 1.697 | 0.119 | 0.344 | 0.848 |
Blood loss [mL, mean(SD)] | 185.2 | 162.0 | 159.5 | 216.8 | 207.9 | 219.8 | 153.8 | 0.715 | 0.638 | 0.336 | 0.649 |
Placement time of closed thoracic drainage tube (days, median) | 6 | 5 | 5 | 5 | 4 | 5 | 4 | 0.528 | 0.787 | 0.344 | 0.848 |
ICU admission days (days, median) | 3 | 2 | 2 | 2 | 2 | 2 | 2 | 0.401 | 0.878 | 0.415 | 0.798 |
In-hospital days (days, median) | 11 | 11 | 11 | 11 | 8 | 9 | 9 | 0.510 | 0.801 | 1.001 | 0.407 |
Hospitalization costs [Yuan, mean (SD)] | 71 072.9 (81 904.9) | 61 959.2 (31 302.4) | 63 165.9 (27 290.2) | 67 739.4 (36 379.9) | 64 668.7 (32 870.4) | 63 123.6 (33 953.1) | 60 546.8 (30 060.6) | 0.599 | 0.732 | 0.336 | 0.854 |
30-day mortality (%)# | 2.8 | 1.1 | 2.8 | 2.3 | 5.9 | 5.5 | 1.1 | 4.768 | 0.529 | 3.710 | 0.406 |
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