抗中性粒细胞胞浆抗体相关性血管炎,淀粉样变性," /> 抗中性粒细胞胞浆抗体相关性血管炎,淀粉样变性,"/> <b>Renal </b><b>a</b><b>myloidosis </b><b>s</b><b>econdary to ANCA-</b><b>a</b><b>ssociated </b><b>v</b><b>asculitis</b><b>: a case report</b>

Chinese Medical Sciences Journaldoi: 10.24920/003999

• Case Reports •     Next Articles

Renal amyloidosis secondary to ANCA-associated vasculitis: a case report

Xin He1, Jianping Ning2, Hui Xu2, Gong Xiao2, Huixiang Yang1, Weiyuan Wang3, Xiaoying Wu3, Hongling Yin3, Xiaozhao Li2*   

  1. 1Department of Gastroenterology, 2Department of Nephrology, 3Department of Pathology, Xiangya Hospital, Central South University, Changsha 410008, China

Abstract: Renal amyloidosis secondary to anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is extremely rare. Here, we reported a 77-year-old woman with ANCA-associated vasculitis. Renal biopsy with Masson trichrome staining showed pauci-immune crescentic glomerulonephritis, and electron microscopy showed amyloid deposition in the mesangial area. Immunofluorescence revealed kappa light chain and lambda light chain were negative. Bone marrow biopsy revealed no clonal plasma cell. Finally, she was diagnosed as ANCA-associated vasculitis with secondary renal amyloid A amyloidosis.

Key words: anti-neutrophil cytoplasmic antibody-associated vasculitis, amyloidosis

Copyright © 2021 Chinese Academy of Medical Sciences.  京公安备110402430088  京ICP备06002729号-1  Powered by Magtech.

Supervised by National Health & Family Plan Commission of PRC

9 Dongdan Santiao, Dongcheng district, Beijing, 100730 China

Tel: 86-10-65105897  Fax:86-10-65133074 

E-mail: cmsj@cams.cn  www.cmsj.cams.cn

Copyright © 2018 Chinese Academy of Medical Sciences

All right reserved.

京公安备110402430088  京ICP备06002729号-1