Chinese Medical Sciences Journal ›› 2011, Vol. 26 ›› Issue (4): 257-258.doi: 10.1016/S1001-9294(12)60013-3

• NEW TECHNIQUE • Previous Articles    

Modified Approach for Establishing Filament-induced Permanent Middle Cerebral Artery Occlusion Rats and Mice Models

You-xin Ji*, Ke-tao Lan, Chuan-xin Geng, Xiao Zou, and Song-ping Wang   

  1. Department of Medical Oncology, Qingdao Central Hospital, Second Affiliated Hospital of Qingdao University, Qingdao 266042, China
  • Received:2011-05-13 Online:2011-12-30 Published:2011-12-30
  • Contact: Corresponding author Tel: 86-532-68665078, E-mail: 123456789ji@

Abstract: BRAIN ischemia stroke is a devastating disease, with more than 10% stroke patients either severely disabled or dead. Although rodent fil- ament middle cerebral artery occlusion (MCAO) model can mimic human brain ischemic stroke well, its wide use was restricted by difficulty in surgery, especially in ligating pterygopalatine artery (PPA).

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