Chinese Medical Sciences Journal ›› 2013, Vol. 28 ›› Issue (3): 152-158.doi: 10.1016/S1001-9294(13)60041-3

• ORIGINAL ARTICLE • Previous Articles     Next Articles

Assessment of Left Atrial Function by Full Volume Real-time Three-dimensional Echocardiography and Left Atrial Tracking in Essential Hypertension Patients with Different Patterns of Left Ventricular Geometric Models

Yang Wang1, Lin Gao1, *, Jian-bai Li2, Chao Yu3   

  1. 1Department of Ultrasound, Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116027, China; 2Department of Ultrasound, Panjin Municipal Central Hospital, Panjin, Liaoning 124000, China; 3Department of Ultrasound, Dongguan Municipal People’s Hospital, Dongguan, Guangdong 523059, China
  • Received:2013-02-15 Published:2013-09-30 Online:2013-09-30
  • Contact: *Corresponding author Tel: 86-411-84671291-2413, E-mail:

Methods One hundred and thirty-three patients with essential hypertension were divided into four groups according to criteria proposed by Ganau et al: 36 patients in normal pattern group (I), 34 patients in concentric remodelling pattern group (II), 33 patients in concentric hypertrophy pattern group (III), and 30 patients in eccentric hypertrophy pattern group (IV). Thirty-two healthy volunteers were enrolled in this study. RT-3DE and LAT were used to obtain the volume-time and emptying fraction curves, and then the maximal volume, minimal volume, stroke volume, presystolic volume, ejection fraction, systolic filling rate, early diastolic emptying rate and late diastolic emptying rate of the left atrium were measured. Conduit volume and passive emptying volume of the left atrium were calculated.Results Left atrial indexes, conduit volume, passive emptying volume, and early diastolic emptying rate decreased, while the other indices increased in the group I compared with the control group (all P<0.05). Compared with the control group, I and II groups, the left atrial volume parameters manifested change in the group III and group IV (all P<0.01). Left atrial ejection fraction measured by RT-3DE or LAT, and late diastolic emptying rate were lower in the group IV compared with the group III (all P<0.05). There was no difference in left atrial conduit volume, passive emptying volume, and early diastolic left atrial emptying rate between the group II and group I (all P>0.05). There was a positive correlation between RT-3DE and LAT in evaluating left atrial function.Conclusions Left atrial booster pump function decreases in the eccentric hypertrophy pattern. Left atrial conduit function is unchanged in the normal pattern and the concentric remodelling pattern groups. RT-3DE and LAT technology can be used for quantitative evaluation of left atrial volume and function.

Key words: essential hypertension, left atrial function, three-dimensional echocardiography, left atrial tracking

Funding: △Supported by the Natural Science Foundation of Liaoning Province, China (2013023010).

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