Chinese Medical Sciences Journal ›› 2012, Vol. 27 ›› Issue (4): 225-231.doi: 10.1016/S1001-9294(13)60006-1

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Intravenous Contrast Material Administration at High-pitch Dual-source CT Coronary Angiography: Bolus-tracking Technique with Shortened Time of Respiratory Instruction Versus Test Bolus Technique

Kai Sun1*, Guo-rong Liu1, Yue-chun Li1, Rui-juan Han2, Li-fang Cui1, Li-jun Ma1, Li-gang Li3, Chang-yong Li4   

  1. 1Department of Radiology; 2Department of Cardiology, Baotou Central Hospital, Baotou 014040, China; 3CT BM Clinic Marketing, Siemens Healthcare, Beijing 100102, China; 4Department of Physiology, School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China
  • Received:2012-05-13 Published:2013-01-07 Online:2013-01-07
  • Contact: *Corresponding author Tel: 86-13654844693, E-mail:
  • About author:*Corresponding author Tel: 86-13654844693, E-mail:

Objective To investigate the feasibility of acquiring the similar homogeneous enhancement using bolus-tracking techniques with shortened respiratory time in prospectively electrocardiogram-gated high-pitch spiral acquisition mode (Flash mode) coronary computed tomography angiography (CCTA) compared with test bolus technique. Methods One hundred and eighty-four consecutive patients with mean heart rate ≤65 beats per minute undergoing CCTA were prospectively included in this study. The patients were randomly divided into two groups. Patients in the group A (n=92) instructed to shorten respiratory time received CCTA using bolus-tracking technique with high-pitch spiral acquisition mode (Flash mode), while those in the group B (n=92) underwent CCTA with test bolus technique. The attenuation in the ascending aorta, image noise, contrast-to-noise ratio and radiation doses of the two groups were assessed. Results There were no significant differences in the mean attenuation values in the ascending aorta (483.18±59.07 HU vs. 498.7±83.51 HU, P=0.183), image noise (21.4±4.5 HU vs. 20.9±4.3 HU, P=0.414), contrast-to-noise ratio (12.1±4.2 vs. 13.8±5.1, P=0.31) between the groups A and B. There were no significant differences in the radiation dose of dynamic monitoring scans (0.056±0.026 mSv vs. 0.062±0.018 mSv, P=0.068) and radiation dose of angiography (0.94±0.07 mSv vs. 0.96±0.15 mSv, P=0.926) between the two groups, while 15 mL less contrast material volume was administered in the group A than the group B. Conclusion Bolus-tracking technique with shortened time of respiratory in Flash mode of dual-source CT yields the similar homogeneous enhancement with less contrast material in comparison to the test bolus technique.

Key words: dual-source computed tomography, coronary angiography, contrast, enhancement, test bolus technique, bolus-tracking technique


△Supported by the Ministry of Science and Technology of Inner Mongolia, China (20110504).

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