Chinese Medical Sciences Journal ›› 2016, Vol. 31 ›› Issue (1): 65-68.doi: 10.1016/S1001-9294(16)30026-8

• REVIEW • Previous Articles    

Effect of Autophagy Over Liver Diseases

Dong-qian Yi1, Xue-feng Yang1, *, Duan-fang Liao2, Qing Wu1, Nian Fu1, Yang Hu1, Ting Cao1   

  1. 1Department of Digestion Internal Medicine, the Affiliated Nanhua Hospital of University of South China, Hengyang 421000, Hunan, China;
    2Department of Pathology, Hunan University of Chinese Medicine, Changsha 410208, China
  • Received:2015-08-16 Published:2016-03-20 Online:2016-03-20
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In recent years, increasingly evidences show that autophagy plays an important role in the pathogenesis and development of liver diseases, and the relationship between them has increasingly become a focus of concern. Autophagy refers to the process through which the impaired organelles, misfolded protein, and intruding microorganisms is degraded by lysosomes to maintain stability inside cells. This article states the effect of autophagy on liver diseases (hepatic fibrosis, fatty liver, viral hepatitis, and liver cancer), which aims to provide a new direction for the treatment of liver diseases.

Key words: autophagy, hepatic fibrosis, fatty liver, viral hepatitis, liver cancer

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