Chinese Medical Sciences Journal ›› 2016, Vol. 31 ›› Issue (1): 62-64.doi: 10.1016/S1001-9294(16)30025-6

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Roles of Long-chain Acyl Coenzyme A Synthetase in Absorption and Transport of Fatty Acid

Fan Gao1, Xue-feng Yang1, *, Nian Fu1, Yang Hu1, Yan Ouyang2, Kai Qing2   

  1. 1Department of Gastroenterology, the Affiliated Nanhua Hospital of University of South China, Hengyang 421002, Hunan, China;
    2Department of Nephrology,
    3Department of Hematology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Received:2015-09-25 Online:2016-03-20 Published:2016-03-20
  • Contact: Tel: 86-13874934270, Fax: 86-734-8358399, E-mail: yxf9988@126.com
  • Supported by:
    △Supported by the National Natural Science Foundation of China (81373465)

Abstract: Long-chain acyl coenzyme A synthetase (ACSL) is a member of the synthetase family encoded by a multigene family; it plays an important role in the absorption and transport of fatty acid. Here we review the roles of ACSL in the regulating absorption and transport of fatty acid, as well as the connection between ACSL and some metabolic diseases.

Key words: long-chain acyl coenzyme A synthetase, fatty acid, absorption, transport

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