The Effect of Sleep Deprivation on Coronary Heart Disease△

doi:10.1016/S1001-9294(17)30008-1

Abstract

Sleep deprivation (SD) has been associated with an increased morbidity and mortality of coronary heart disease (CHD). SD could induce autonomic nervous dysfunction, hypertension, arrhythmia, hormonal dysregulation, oxidative stress, endothelial dysfunction, inflammation and metabolic disorder in CHD patients. This paper reviewed the study results of SD in clinical trials and animal experiments and concluded that SD was associated with cardiovascular risk factors, which aggravated CHD in pathogenesis and outcomes.

Key words: heart disease, insomnia, sleep disorder, risk factors, myocardial ischemia

Rong Yuan, Jie Wang, Li-li Guo. The Effect of Sleep Deprivation on Coronary Heart Disease[J].Chinese Medical Sciences Journal, 2016, 31(4): 247-253.

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