Chinese Medical Sciences Journaldoi: 10.24920/004065

• Original Articles •     Next Articles

Association between Air Pollution and Type 2 Diabetes Mellitus in Developing Countries: A Systematic Review and Meta-Analysis

Zihan Chen#1, Zhou Zhao#1, 2, Chuiwen Deng3, Naishi Li1*   

  1. 1 Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College Hospital, Beijing 100730, China.
    2 Beijing Aerospace General Hospital, Cadre Medical Department, Beijing 100076, China.
    3 Department of Rheumatology & Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, the Ministry of Education Key Laboratory, Beijing 100730, China.

    # Co-first authors.

    * Corresponding author.

  • Received:2022-01-20 Revised:2022-05-22 Accepted:2022-07-01 Published:2022-06-20 Online:2022-06-20

Objective In recent years, many studies have reported that air pollution is a risk factor for type 2 diabetes mellitus (T2DM). The aim of this systematic review and meta-analysis is to summarize the evidence about the association between exposure to air pollution and T2DM in developing countries.
Methods The databases, including PubMed, EMBASE and Web of Science, were systematically searched for studies published up to 31 March 2022. Studies about the association between air pollution and T2DM prevalence or incidence in developing countries were included. The odds ratio (OR) was used as effect estimate. We synthesized the included studies in meta-analyses.
Results We included 8 cross-sectional studies and 8 cohort studies, all conducted in developing countries. Meta-analyses of 8 studies on PM2.5 (particulate matter ≤ 2.5 μm in diameter) showed that the overall effect estimate of T2DM prevalence upon exposure to PM2.5 was 1.12 (95% CI: 1.07, 1.17). The association between air pollutants and T2DM incidence was not estimated due to the limited relevant studies.
Conclusions The exposure to PM2.5 would be positively associated with an increased prevalence of T2DM in developing countries. Some effective measures should be taken to reduce air pollution exposure in people who are vulnerable to diabetes.

Key words: Air pollutants, PM2.5, Type 2 diabetes mellitus

Copyright © 2021 Chinese Academy of Medical Sciences.  京公安备110402430088  京ICP备06002729号-1  Powered by Magtech.

Supervised by National Health & Family Plan Commission of PRC

9 Dongdan Santiao, Dongcheng district, Beijing, 100730 China

Tel: 86-10-65105897  Fax:86-10-65133074 


Copyright © 2018 Chinese Academy of Medical Sciences

All right reserved.

京公安备110402430088  京ICP备06002729号-1