Chinese Medical Sciences Journal ›› 2012, Vol. 27 ›› Issue (4): 243-248.doi: 10.1016/S1001-9294(13)60009-7

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Epidemiology of Hepatitis B and Associated Liver Diseases in China

Yao Zhang1, Hua Zhang2, Au Elizabeth3, Xiao-qing Liu1*   

  1. 1Department of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China; 2Office of Research Adminstration, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China; 3Department of Medicine, Tufts University School of Medicine, Boston 02111, USA
  • Received:2012-05-23 Published:2013-01-07 Online:2013-01-07

Abstract Hepatitis B virus (HBV) infection has long been a critical public health challenge in China. National surveys revealed a prevalence of approximate 10% for chronic HBV infection in general population. HBV has been the leading cause of chronic hepatitis, cirrhosis, and liver cancers in Chinese population and a common pathogen of acute viral hepatitis. Meanwhile, the epidemic provided important opportunities to research the natural history, public health impact, and therapeutic and preventive interventions for HBV in China. In this review, we summarized the selected key epidemiological studies since 1970s regarding HBV infection and its associated liver diseases in China, and provided considerations for future research, prevention and treatment of HBV.

Key words: hepatitis B, epidemiology, cirrhosis, hepatocellular carcinoma

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