Chinese Medical Sciences Journal ›› 2021, Vol. 36 ›› Issue (1): 57-65.doi: 10.24920/003737

• Review • Previous Articles     Next Articles

Research Progress in Targeted Therapy of Hepatocellular Carcinoma

Qiong Chen, Xuefeng Yang()   

  1. Department of Gastroenterology, the Affiliated Nanhua Hospital, University of South China, Hengyang, Hunan Province 421002, China
  • Received:2020-03-06 Accepted:2020-05-11 Published:2021-03-31
  • Contact: Xuefeng Yang

Hepatocellular carcinoma (HCC) is one of the most common malignancies, and its treatment is limited. With the understanding of key genes and signaling pathways in the occurrence and development of HCC, targeted drugs with high selectivity and low toxicity have been developed continuously, bringing a variety of options for the treatment of advanced HCC. In this article, the research progress on representative drugs of targeted therapy and potential therapeutic targets for HCC are reviewed.

Key words: hepatocellular carcinoma, targeted therapy, genes, signaling pathway, drug

Funding: Funded by the Research Project 2017 of Health and Family Planning Commission of Hunan Province(A2017015)

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