Chinese Medical Sciences Journal ›› 2014, Vol. 29 ›› Issue (4): 236-238.doi: 10.1016/S1001-9294(14)60077-8

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Characteristics of PVT1 and Its Roles in Diseases

Li Wang, Jin-hua He*, Ze-ping Han   

  1. Department of Laboratory, Panyu Central Hospital, Guangzhou 511400, China
  • Received:2014-07-03 Published:2014-11-28 Online:2014-11-28
  • About author:**Corresponding author Tel: 86-20-34858851, E-mail:

LONG non-coding RNAs (lncRNAs) are a class of RNAs whose transcripts are longer than 200 nt. These molecules do not encode proteins but have a structure resembling that of mRNA and show polyA tails and promoter structure through splicing. Most lncRNAs show a distinct spatial and temporal specificity during histological differentiation and development. Dynamic expression and different splicing methods may appear during the differentiation process.

Key words: long non-coding RNAs, plasmacytoma variant translocation 1 gene, expression, characteristics

Funding: Supported by Science and Technology Plan of Guangdong Provincial Department of Science and Technology (2011B031800012)

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